| Identification | Back Directory | [Name]
N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide | [CAS]
1139453-98-7 | [Synonyms]
Nintedanib-003
Intedanib Impurity 12
Nintedanib Intermediate 1
N,4-Dimethyl-N-(4-nitrophenyl)-1-piperazineacetamide
1-Piperazineacetamide, N,4-dimethyl-N-(4-nitrophenyl)-
N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acet...
N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide
N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetami...
N,4-Dimethyl-N-(4-Nitrophenyl)-1-Piperazineacetamide(Under Development)
Nintedanib impurity 2/N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
Nidanib Impurity 12: N-methyl-2- (4-methylpiperazin-1-yl) -N- (4-nitrophenyl) -acetamide | [Molecular Formula]
C14H20N4O3 | [MDL Number]
MFCD18207135 | [MOL File]
1139453-98-7.mol | [Molecular Weight]
292.33 |
| Chemical Properties | Back Directory | [Melting point ]
94 - 96°C | [Boiling point ]
446.9±40.0 °C(Predicted) | [density ]
1.230 | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.43±0.10(Predicted) | [color ]
Pale Yellow to Light Yellow |
| Hazard Information | Back Directory | [Uses]
N-Methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide is used as a reactant in the synthetic preparation of 6-methoxycarbonyl-substituted indolinones, such as Intedanib (I666650), which is a triple angiokinase inhibitor and antitumor agent. |
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