| Identification | Back Directory | [Name]
SAMS PEPTIDE | [CAS]
125911-68-4 | [Synonyms]
SAMStide
SAMS PEPTIDE
HMRSAMSGLHLVKRR
HIS-MET-ARG-SER-ALA-MET-SER-GLY-LEU-HIS-LEU-VAL-LYS-ARG-ARG
H-HIS-MET-ARG-SER-ALA-MET-SER-GLY-LEU-HIS-LEU-VAL-LYS-ARG-ARG-OH
(SER76,ARG86,87)-ACC-ALPHA (73-87) (DEPHOSPHORYLATED) (E COLI, RAT)
(SER77,ARG87,88)-ACC-ALPHA (74-88) (DEPHOSPHORYLATED) (BOVINE, OVINE)
(SER76,ARG86,87)-ACETYL-COA CARBOXYLASE 1 (73-87) (DEPHOSPHORYLATED) (E COLI, RAT)
(SER77,ARG87,88)-ACETYL-COA CARBOXYLASE 1 (74-88) (DEPHOSPHORYLATED) (BOVINE, OVINE)
L-Arginine,L-histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-serylglycyl-L-leucyl-L-histidyl-L-leucyl-L-valyl-L-lysyl-L-arginyl-
(Ser76,Arg86·87)-ACC-a (73-87) (dephosphorylated) (E. coli, rat), (Ser76,Arg86·87)-Acetyl-CoA Carboxylase 1 (73-87) (dephosphorylated) (E. coli, rat), (Ser77,Arg87·88)-ACC-a (74-88) (dephosphorylated) (bovine, ovine), (Ser77,Arg87·88)-Acetyl-CoA Carboxylase 1 (74-88) (dephosphorylated) (bovine, ovine) | [Molecular Formula]
C74H131N29O18S2 | [MDL Number]
MFCD02682924 | [MOL File]
125911-68-4.mol | [Molecular Weight]
1779.15 |
| Chemical Properties | Back Directory | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [solubility ]
DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
powder | [color ]
white to off-white |
| Hazard Information | Back Directory | [General Description]
SAMS Peptide trifluoroacetate salt is a peptide having a putative AMPK phosphorylation site (Ser568) of carbohydrate-responsive element-binding protein (ChREBP) and a peptide containing a cAMP-dependent protein kinase (PKA) phosphorylation site (Thr666). | [Biochem/physiol Actions]
SAMS Peptide is a synthetic substrate selective for AMP-activated protein kinase (AMPK). Its sequence is based on acetyl-CoA carboxylase, which is phosphorylated exclusively by the AMPK, but with serine (Ser)-79 replaced by alanine SAMS peptide is more specific for AMPK than acetyl-CoA carboxylase itself. | [storage]
Desiccate at -20°C |
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