| Identification | Back Directory | [Name]
Acid-PEG5-t-butyl ester | [CAS]
1309460-29-4 | [Synonyms]
COOH-PEG5-OtBu
COOH-PEG5-COOtBu
Acid-PEG5-C2-Boc
Acid-PEG5-t-butyl ester
HOOCCH2CH2O-PEG4-CH2CH2COOtBu
4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester | [Molecular Formula]
C18H34O9 | [MDL Number]
MFCD18916989 | [MOL File]
1309460-29-4.mol | [Molecular Weight]
394.46 |
| Chemical Properties | Back Directory | [Boiling point ]
495.2±45.0 °C(Predicted) | [density ]
1.109±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [pka]
4.28±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Acid-PEG5-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. |
|
|