Log in | Join Free | china | japan | germany
ChemicalBook--->CAS DataBase List--->141282-35-1

141282-35-1

Request For Quotation
141282-35-1 Structure

141282-35-1 Structure
IdentificationBack Directory
[Name]

H2N-PEG5-CH2COOH
[CAS]

141282-35-1
[Synonyms]

Amino-PEG5
141282-35-1
H2N-PEG5-CH2COOH
NH2-PEG5-CH2COOH
Amino-PEG5-CH2COOH
Amino-PEG5-CH2CO2H
AMINE-PEG5-CH2COOH
Amino-PEG5-CH2CO5H
Amino-PEG5-acetic acid
2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]aceticacid
[Molecular Formula]

C12H25NO7
[MDL Number]

MFCD27977526
[MOL File]

141282-35-1.mol
[Molecular Weight]

295.33
Chemical PropertiesBack Directory
[solubility ]

DMSO : 20 mg/mL (67.72 mM; ultrasonic and warming and heat to 60°C)
Hazard InformationBack Directory
[Biological Activity]

Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
141282-35-1 suppliers list
Company Name: 9i LLC
Tel: +18039569191
Website: www.nineilab.com
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-61398051 +8613650506873 , +8613650506873
Website: http://www.chemdad.com/
Company Name: career henan chemical co
Tel: +86-0371-86658258 15093356674; , 15093356674;
Website: http://www.coreychem.com
Company Name: SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel: +86-021-61551413 +8618813727289 , +8618813727289
Website: www.trustwe.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439 , +8613336028439
Website: http://www.nextpeptide.com/
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207 , +8617767106207
Website: https://www.molcore.com/
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203 , +undefined18143011203
Website: www.chemextension.com/
Company Name: Xian confluore Biological Technology Co., Ltd.
Tel: +86-15680926068 +86-15680926068 , +86-15680926068
Website: http://www.confluore.com/
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Website: https://www.aladdinsci.com/
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Website: https://www.aladdinsci.com/
Company Name: Biomatrik (Jiaxing) Inc.  
Tel: 573-573-82623377 18967387295
Website: http://www.biomatrik.com
Company Name: T&W GROUP  
Tel: 021-61551611 13296011611
Website: www.trustwe.com/
Company Name: Nanjing Anyan Pharmaceutical Technology Co. , Ltd.  
Tel: 025-5836128; 18136859766
Website: https://www.chemicalbook.com/productlist.aspx?cbn=CB0386760
Company Name: Hunan HuaTeng Pharmaceutical Co., Ltd.,  
Tel: 400-8592883 15367835770
Website: http://www.huatengsci.com
Company Name: Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.  
Tel: 025-66113011 18112977050
Website: http://www.aikonchem.com
Company Name: Tongling HengYou Biotechnology Co., Ltd.  
Tel: 021-50426030 13856289449
Website: www.chemicalbook.com/ShowSupplierProductsList16800/0.htm
Tags:141282-35-1 Related Product Information
195071-49-9 663921-15-1 1818294-41-5 352439-37-3 756526-04-2 1425973-14-3 39160-70-8 791028-27-8 784105-33-5 34188-11-9 905954-28-1 86770-74-3 129449-09-8 1186194-33-1 6338-55-2