| Identification | Back Directory | [Name]
Azide-PEG3-Desthiobiotin | [CAS]
1426828-06-9 | [Synonyms]
CAS_1426828-06-9
Desthiobiotin-PEG4-Azide
Azide-PEG3-Desthiobiotin
N-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide | [Molecular Formula]
C18H34N6O5 | [MOL File]
1426828-06-9.mol | [Molecular Weight]
414.51 |
| Hazard Information | Back Directory | [Description]
Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd?= 1011?vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. |
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| Company Name: |
TCI Europe
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| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
| Company Name: |
TCI AMERICA
|
| Tel: |
800-4238616 |
| Website: |
https://www.tcichemicals.com/en/us/index.html |
| Company Name: |
TCI Chemicals
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| Tel: |
021-67121386, 800-988-0390 |
| Website: |
www.tcichemicals.com |
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