| Identification | Back Directory | [Name]
2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide | [CAS]
1486482-16-9 | [Synonyms]
2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide | [Molecular Formula]
C17H13Cl2N3O4S | [MDL Number]
MFCD28411402 | [MOL File]
1486482-16-9.mol | [Molecular Weight]
426.274 |
| Hazard Information | Back Directory | [Biological Activity]
ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1].
ML251 (T. brucei; 0~33.3 μg/mL) produces modest dose-dependent toxicity[1]. | [References]
[1]. Brimacombe KR, et al. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett. 2013;5(1):12-17. |
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InvivoChem
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