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151889-03-1

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151889-03-1 Structure

151889-03-1 Structure
IdentificationBack Directory
[Name]

2-PHENYLMELATONIN
[CAS]

151889-03-1
[Synonyms]

2-PHENYLMELATONIN
Melatonin Impurity 11
Melatonin 2-Phenyl Impurity
N-[2-(5-METHOXY-2-PHENYLINDOL-3-YL)ETHYL]ACETAMIDE
N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide
Acetamide, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]-
[Molecular Formula]

C19H20N2O2
[MDL Number]

MFCD00673896
[MOL File]

151889-03-1.mol
[Molecular Weight]

308.37
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at +4°C
[solubility ]

Soluble to 100 mM in ethanol and to 100 mM in DMSO
[form ]

Powder
Hazard InformationBack Directory
[Uses]

2-Phenylmelatonin is a melatonin receptor binder with mixed agonist/antagonist activity.
[Definition]

ChEBI: N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide is a phenylindole.
[Synthesis Reference(s)]

Journal of Medicinal Chemistry, 38, p. 1132, 1995 DOI: 10.1021/jm00007a010
[Biological Activity]

Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC 50 values for G protein activation in MT 1 and MT 2 -transfected cells are 65 and 58 pM respectively.
[storage]

Desiccate at +4°C
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