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152175-74-1

152175-74-1 Structure

152175-74-1 Structure
IdentificationBack Directory
[Name]

bequinostatin C
[CAS]

152175-74-1
[Synonyms]

bequinostatin C
Benzo[a]naphthacene-2-carboxylic acid, 8,13-dihydro-1,7,9,11-tetrahydroxy-8,13-dioxo-3-pentyl-
[Molecular Formula]

C28H22O8
[MOL File]

152175-74-1.mol
[Molecular Weight]

486.47
Chemical PropertiesBack Directory
[solubility ]

DMSO: Slightly soluble; Methanol: Slightly soluble
[form ]

A solid
Hazard InformationBack Directory
[Description]

Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50 = 40 μg/ml for human GSTP1).1
[References]

1. Yamazaki, T., Tatee, T., Aoyama, T., et al. Bequinostatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12 J. Antibiot. (Tokyo) 46(8),1309-1311(1993).
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