ChemicalBook--->CAS DataBase List--->1628047-87-9

1628047-87-9

1628047-87-9 Structure

1628047-87-9 Structure
IdentificationBack Directory
[Name]

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride
[CAS]

1628047-87-9
[Synonyms]

abt199 int 1
5-dimethyl-3
1-((4-chloro-5
ABT199 intermediate1
ABT-199 Intermeidate1
Venetoclax Intermediate 2
1-biphenyl]-2-yl)methyl)piperazine dihydrochloride
1-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]piperazine diHCL
1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine hydrochloride
1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine dihydrochloride
1-[[2-(4-chlorophenyl)-4,4-dimethyl-cyclohexen-1-yl]methyl]piperazine dihydrochloride
1-{[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl}piperazine dihydrochloride
1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride
1-((4-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 2HCl
Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]- (Dihydrochloride)
1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl] methyl]-Piperazine, hydrochloride (1:2)
1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydroch
Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (1:2)
1-((4'-chloro-5,5-demethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl-2yl]methyl)piperazine dihydrochloride
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride
1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrah ydro-[1,1'-biphenyl]-2-yl)methy)piperazine dihydrochloride
[Molecular Formula]

C19H27ClN2.2(HCl)
[MDL Number]

MFCD28334264
[MOL File]

1628047-87-9.mol
[Molecular Weight]

391.806
Chemical PropertiesBack Directory
[storage temp. ]

Inert atmosphere,Room Temperature
[CAS DataBase Reference]

1628047-87-9
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H335-H319-H315
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard InformationBack Directory
[Uses]

1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine Dihydrochloride is an intermediate used in the preparation of Venetoclax (A112430), which is a potent and selective BCL-2 inhibitor with potent antitumour activity while sparing platelets. Venetoclax is used to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.
Spectrum DetailBack Directory
[Spectrum Detail]

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride(1628047-87-9)1HNMR
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