Identification | Back Directory | [Name]
Deracoxib | [CAS]
169590-41-4 | [Synonyms]
Sc 46 DeraM Sc 59046 Deramaxx Deracoxib Deracoxib-d3 Unii-vx29jb5xwv Deracoxib [usan] 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)pyrazol-1-yl]benzenesulfonamide 4-(3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide 4-[5-(3-Fluoro-4-Methoxyphenyl)-3-(difluoroMethyl)-1H-pyrazol-1-yl]benzenesulfonaMide Benzenesulfonamide, 4-3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl- | [EINECS(EC#)]
807-307-6 | [Molecular Formula]
C17H14F3N3O3S | [MDL Number]
MFCD09837763 | [MOL File]
169590-41-4.mol | [Molecular Weight]
397.37 |
Chemical Properties | Back Directory | [Melting point ]
159-161° | [Boiling point ]
575.5±60.0 °C(Predicted) | [density ]
1.48 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Acetonitrile (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
9.69±0.10(Predicted) | [color ]
Light Brown |
Hazard Information | Back Directory | [Uses]
Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low dose
s, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation. | [Definition]
ChEBI: A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3, and 5 by 4-sulfamoylphenyl, difluoromethyl and 3-fluoro-4-methoxyphenyl groups, respectively. A selective cyclooxygenase 2 inhibitor, it is us
d in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in dogs. | [Veterinary Drugs and Treatments]
Deracoxib is indicated for the treatment of post-operative pain
(higher dose, 7 day maximum), and for the treatment of pain and
inflammation associated with osteoarthritis (lower dose, ongoing
dosing) in dogs.
Like piroxicam, deracoxib is of interest in adjunctive treatment
of transitional cell carcinoma of the bladder; investigations into this
use are ongoing. | [storage]
Store at -20°C |
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