| Identification | Back Directory | [Name]
ethiazide | [CAS]
1824-58-4 | [Synonyms]
Salta
Etizide
ethiazide
Eclotizide
aethiazidum
Eclotizidum
Neo Diuresal
6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-ethyl-3,4-dihydro-, 1,1-dioxide
6-chloro-3-ethyl-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide | [EINECS(EC#)]
217-358-0 | [Molecular Formula]
C9H12ClN3O4S2 | [MDL Number]
MFCD00867314 | [MOL File]
1824-58-4.mol | [Molecular Weight]
325.79 |
| Hazard Information | Back Directory | [Originator]
Ethiazide,Tokyo Tanabe,Japan,1970 | [Definition]
ChEBI: Ethiazide is a benzothiadiazine. | [Manufacturing Process]
A mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of
anhydrous diethylene glycoldimethylether, 0.44 gram of propionaldehyde and
0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams
hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at
that temperature for 1 hour. The reaction mixture is concentrated under
reduced pressure; on addition of water, the product separates and is then
recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3-
ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to
270°C. | [Therapeutic Function]
Diuretic, Cardiotonic, Smooth muscle relaxant,
Respiratory stimulant |
|
| Company Name: |
Matrix Scientific
|
| Tel: |
803 788-9494 All other calls |
| Website: |
www.matrixscientific.com |
|