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191102-87-1

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191102-87-1 Structure

191102-87-1 Structure
IdentificationBack Directory
[Name]

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
[CAS]

191102-87-1
[Synonyms]

GGTI-2147
GGTI-2147 (GGTI2147)
TUQRZGWNDBXSNP-SANMLTNESA-N
Geranylgeranyl transferase inhibitor-2147
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
[Molecular Formula]

C28H30N4O3
[MDL Number]

MFCD22581512
[MOL File]

191102-87-1.mol
[Molecular Weight]

470.56
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO
[form ]

Solid
[Sensitive ]

Light Sensitive & Hygroscopic
Hazard InformationBack Directory
[Uses]

GGTI-2147 is an inhibitors of protein geranylgeranyltransferase-I and protein prenylation. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast and increases cytosolic accumulation of Rac1 and elicites significant inhibition of GSIS from INS 832/13 cells.
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