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1936429-06-9

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1936429-06-9 Structure

1936429-06-9 Structure
IdentificationBack Directory
[Name]

tert-butyl 3-bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate(WX142184)
[CAS]

1936429-06-9
[Synonyms]

3-Bromo-5-Boc-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine
tert-butyl 3-bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
tert-Butyl 3-bromo-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
tert-butyl 3-bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate(WX142184)
5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 3-bromo-1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester
[Molecular Formula]

C11H16BrN3O2
[MDL Number]

MFCD30751004
[MOL File]

1936429-06-9.mol
[Molecular Weight]

302.17
Chemical PropertiesBack Directory
[solubility ]

Dichloromethane; Ethyl Acetate; Methanol
[form ]

Solid
[color ]

Light Green
Hazard InformationBack Directory
[Uses]

tert-Butyl 3-Bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.
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