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2113650-03-4

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2113650-03-4 Structure

2113650-03-4 Structure
IdentificationBack Directory
[Name]

BMS-1001
[CAS]

2113650-03-4
[Synonyms]

BMS-1001
D-Serine, N-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methyl]-
[Molecular Formula]

C35H34N2O7
[MDL Number]

MFCD32709962
[MOL File]

2113650-03-4.mol
[Molecular Weight]

594.65
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 50 mg/mL (84.08 mM);Ethanol: Insoluble
[Water Solubility ]

Water: Insoluble
Hazard InformationBack Directory
[Uses]

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction (IC50: 2.25 nM in a homogeneous time-resolved fluorescence binding assay).
[Biological Activity]

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. It attenuates the inhibitory effect of soluble PD-L1 on T cell receptor-mediated T lymphocyte activation.
[target]

TargetValue
PD-1/PD-L1
(Cell-free assay) 		253 nM(EC50)
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

BMS-1001(2113650-03-4)1HNMR
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