ChemicalBook--->CAS DataBase List--->3012-71-3

3012-71-3

3012-71-3 Structure

3012-71-3 Structure
IdentificationBack Directory
[Name]

6-FITC
[CAS]

3012-71-3
[Synonyms]

6-FITC
FITC ISOMER II
FITC 'ISOMER II'
6-FITC USP/EP/BP
Fluorescein isothioc
6-ISOTHIOCYANATO-FLUORESCEIN
FLUORESCEIN 6-ISOTHIOCYANATE, ISOMER 2
FLUORESCEIN ISOTHIOCYANATE (ISOMER II)
Fluorescein 6-isothiocyanate≥ 95% (HPLC)
Anti-Cat IgG (H+L)-Fluorescein antibody produced in goat
Anti-Pig IgG (H+L)-Fluorescein antibody produced in goat
Anti-Dog IgG (H+L)-Fluorescein antibody produced in goat
Anti-Rat IgG (H+L)-Fluorescein antibody produced in sheep
Anti-goat IgG (H+L)-Fluorescein antibody produced in mouse
Anti-Rat IgG (H+L)-Fluorescein antibody produced in donkey
Anti-Horse IgG (H+L)-Fluorescein antibody produced in goat
Anti-Swine IgG (H+L)-Fluorescein antibody produced in goat
Anti-Cat IgG (H+L)-Fluorescein antibody produced in rabbit
Anti-Human IgG (H+L)-Fluorescein antibody produced in sheep
Anti-goat IgG (H+L)-Fluorescein antibody produced in donkey
Anti-Rat IgG (H+L)-Fluorescein antibody produced in chicken
Anti-Donkey IgG (H+L)-Fluorescein antibody produced in goat
Anti-Mouse IgG (H+L)-Fluorescein antibody produced in sheep
Anti-Rabbit IgG (H+L)-Fluorescein antibody produced in sheep
Anti-Human IgG F(ab′)2-Fluorescein antibody produced in goat
Anti-Mouse IgG F(ab′)2-Fluorescein antibody produced in goat
Anti-Human IgG (H+L)-Fluorescein antibody produced in donkey
Anti-Pig IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Rat IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Mouse IgG (H+L)-Fluorescein antibody produced in donkey
Anti-Mouse IgG (H+L)-Fluorescein antibody produced in rabbit
Anti-Cat IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Dog IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-HAMSTER IgG (H+L)-Fluorescein antibody produced in goat
Anti-goat IgG (H+L)-Fluorescein antibody produced in chicken
Anti-Porcine IgG (H+L)-Fluorescein antibody produced in goat
Anti-Chicken IgG (H+L)-Fluorescein antibody produced in goat
Anti-Horse IgG (H+L)-Fluorescein antibody produced in rabbit
Anti-Horse IgG F(ab′)2-Fluorescein antibody produced in goat
Anti-Goat IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Mouse IgG (H+L)-Fluorescein antibody produced in chicken
Anti-Rabbit IgG (H+L)-Fluorescein antibody produced in donkey
Anti-Bovine IgG F(ab′)2-Fluorescein antibody produced in goat
Anti-Donkey IgG (H+L)-Fluorescein antibody produced in rabbit
Anti-Human IgG (H+L)-Fluorescein antibody produced in chicken
Anti-Rabbit IgG F(ab′)2-Fluorescein antibody produced in goat
Anti-Human IgM (Fc5μ) -Fluorescein antibody produced in rabbit
Anti-Mouse IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-HAMSTER IgG (H+L)-Fluorescein antibody produced in rabbit
Anti-Swine IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Human IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Rabbit IgG (H+L)-Fluorescein antibody produced in chicken
Anti-Horse IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Sheep IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Bovine IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Guinea Pig IgG (H+L)-Fluorescein antibody produced in goat
Anti-Porcine IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Dog IgG (Fc specific)-Fluorescein antibody produced in goat
Anti-Cat IgG (Fc specific)-Fluorescein antibody produced in goat
Anti-Chicken IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Rat IgG (Fc specific)-Fluorescein antibody produced in goat
Anti-Rat IgG IgA IgM (H+L)-Fluorescein antibody produced in goat
Anti-Hamster IgG F(ab′)2-Fluorescein antibody produced in rabbit
2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-4-ISOTHIOCYANATO-BENZOIC ACID
Anti-Guinea Pig IgG (H+L)-Fluorescein antibody produced in rabbit
Anti-Guinea Pig IgG F(ab′)2-Fluorescein antibody produced in goat
Anti-Cat IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Mouse IgG IgA IgM (H+L)-Fluorescein antibody produced in goat
Anti-Rat IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Pig IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Horse IgG (Fc specific)-Fluorescein antibody produced in goat
Anti-Dog IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Guinea Pig IgG F(ab′)2-Fluorescein antibody produced in rabbit
Anti-Rabbit IgG (Fc specific)-Fluorescein antibody produced in goat
Anti-goat IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Ferret IgG IgA IgM (H+L)-Fluorescein antibody produced in goat
Anti-Monkey IgG IgA IgM (H+L)-Fluorescein antibody produced in goat
Anti-Sheep IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Mouse IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Human IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Swine IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Horse IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Rat IgA (α-chain specific)-Fluorescein antibody produced in goat
Anti-Rat IgM (μ-chain specific)-Fluorescein antibody produced in goat
Anti-Bovine IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Mouse (λ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Rabbit IgG (Fc specific)-Fluorescein antibody produced in donkey
Anti-Porcine IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Chicken IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Guinea Pig IgG (Fc specific)-Fluorescein antibody produced in goat
Anti-Rat IgM (μ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Monkey IgM (μ-chain specific)-Fluorescein antibody produced in goat
Anti-Ferret IgM (μ-chain specific)-Fluorescein antibody produced in goat
Anti-Ferret IgG (γ-chain specific)-Fluorescein antibody produced in goat
Anti-Ferret IgA (α-chain specific)-Fluorescein antibody produced in goat
Anti-Monkey IgG (γ-chain specific)-Fluorescein antibody produced in goat
Anti-Monkey IgA (α-chain specific)-Fluorescein antibody produced in goat
Anti-Rat IgG (H+L), F(ab) fragment-Fluorescein antibody produced in goat
Anti-Human IgA (α-chain specific)-Fluorescein antibody produced in rabbit
Anti-Mouse IgG (γ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Human IgG (γ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Chicken IgM (μ-chain specific)-Fluorescein antibody produced in goat
Anti-Guinea Pig IgG (Fc specific)-Fluorescein antibody produced in rabbit
Anti-Mouse IgM (μ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Mouse IgG (H+L), F(ab) fragment-Fluorescein antibody produced in goat
Anti-Mouse IgG1 (γ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Rat IgG (H+L), F(ab) fragment-Fluorescein antibody produced in rabbit
Anti-Human IgG (H+L), F(ab) fragment-Fluorescein antibody produced in goat
Anti-Mouse IgG3 (γ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Rat IgG (H+L), F(ab′)2 fragment-Fluorescein antibody produced in goat
Anti-Mouse IgG2a (γ-chain specific)-Fluorescein antibody produced in rabbit
Anti-Goat IgG (H+L), F(ab) fragment-Fluorescein antibody produced in rabbit
Anti-Mouse IgG2b (γ-chain specific)-Fluorescein antibody produced in rabbit
[Molecular Formula]

C21H11NO5S
[MDL Number]

MFCD00041838
[MOL File]

3012-71-3.mol
[Molecular Weight]

389.38
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[form ]

lyophilized powder
Safety DataBack Directory
[Symbol(GHS) ]


GHS06,GHS09
[Signal word ]

Danger
[Hazard statements ]

H302-H311-H411
[Precautionary statements ]

P280-P301+P312+P330-P302+P352+P312
[Hazard Codes ]

Xi
[Risk Statements ]

36-42/43
[Safety Statements ]

26-45-36/37-22
[WGK Germany ]

3
[HS Code ]

29329990
Hazard InformationBack Directory
[Chemical Properties]

Orange powder
[Uses]

6-FITC is a fluorescent labeling reagent for proteins,it is Used in the fluorescent antibody technique for rapid identification of pathogens.
[General Description]

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a γ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. The Fc fragment contains the CH2 and CH3 domains of the antibody molecule. Pepsin cleaves the carboxy-terminal side of the disulfide bonds in the general region of the antibody and this gives rise to the F(ab′)2 fragment. The two antigen-binding arms of the antibody are linked in this fragment. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants.
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