ChemicalBook--->CAS DataBase List--->352439-36-2

352439-36-2

352439-36-2 Structure

352439-36-2 Structure
IdentificationBack Directory
[Name]

alpha-Azido-omega-hydroxy octa(ethylene glycol)
[CAS]

352439-36-2
[Synonyms]

PEG8-azide
N3-PEG(8)-OH
azido-PEG8-OH
Azido-dPEG??-OH
Azido-PEG (n=7)
Azido-PEG8-alcohol
Azide-PEG8-Alcohol
Azido-PEG7-alcohol
AZIDO-PEG8-HYDROXY
O-(2-Azidoethyl)heptaethylene glycol
alpha-Azido-omega-hydroxy octa(ethylene glycol)
3,6,9,12,15,18,21-heptaoxatricosan-1-ol,23-azide
23-Azido-3,6,9,12,15,18,21-Heptaoxatricosan-1-ol
3,6,9,12,15,18,21-Heptaoxatricosan-1-ol, 23-azido-
O-(2-Azidoethyl)heptaethylene glycol >=95% (oligomer purity)
2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
[Molecular Formula]

C16H33N3O8
[MDL Number]

MFCD08274607
[MOL File]

352439-36-2.mol
[Molecular Weight]

395.45
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

Soluble in Water, DMSO, DCM, DMF
[BRN ]

8940056
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
[HS Code ]

2929900090
Hazard InformationBack Directory
[Description]

Azide-PEG8-alcohol is a click chemistry reagent with an azide(N3) and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl (OH) group enables further derivatization or replacement with other functional groups.
[Uses]

O-(2-Azidoethyl)heptaethylene glycol is used to synthesize oligo and poly(ethylene glycol) derivatives that are used as structural units of dendrimers, hydrogels, surface modifiers, self-assembling systems and molecular crosslinkers. This precursor is compatible for acetylene-azide click reactions.

Some of the reported applications include:
  • Synthesis of strain-stiffening hydrogels through self-assembly of oligomers fibres derived from Azido-PEG (n=7).
  • Synthesis of biodegradable tetra-PEG hydrogels for drug delivery system.
  • Synthesis of heterobifunctional oligo(ethylene glycol) linkers for bioconjugation and targeted drug delivery.
  • Preparation of synthetic amphiphiles for programmed pH-dependent dispersions of carbon nanotubes (CNTs).
  • Selective glycoprotein detection through allosteric click-imprinting by using a self-assembled monolayer developed from the above oligomer.
  • Preparation of bioactivated quantum dot micelles containing fluorescent nanocrystals.

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