ChemicalBook--->CAS DataBase List--->3764-87-2

3764-87-2

3764-87-2 Structure

3764-87-2 Structure
IdentificationBack Directory
[Name]

Trestolone
[CAS]

3764-87-2
[Synonyms]

MENT
TRESTOLONE
7α-Methyl-19-NT
Song holds dragon
Mythyl testosterone
19-nor-7a-methyltestosterone
7α-Methyl-19-nortestosterone
(7R)-17-Hydroxy-7,13-diMethyl-
7-ALPHA-METHYL-19-NORTESTOSTERONE
17β-Hydroxy-7α-methylestr-4-en-3-one
4-ESTREN-7-ALPHA-METHYL-17-BETA-OL-3-ONE
Estr-4-en-3-one,17-hydroxy-7-Methyl-, (7a,17b)-
Estr-4-en-3-one, 17-hydroxy-7-methyl-, (7α,17β)-
(7r)-17-hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-one
[EINECS(EC#)]

227-712-6
[Molecular Formula]

C19H28O2
[MDL Number]

MFCD00271620
[MOL File]

3764-87-2.mol
[Molecular Weight]

288.42
Chemical PropertiesBack Directory
[Melting point ]

145-146 °C
[Boiling point ]

375.48°C (rough estimate)
[density ]

0.9447 (rough estimate)
[refractive index ]

1.6220 (estimate)
[storage temp. ]

Store at -20°C
[pka]

15.06±0.60(Predicted)
[Water Solubility ]

92mg/L(37 ºC)
Hazard InformationBack Directory
[Description]

Trestolone, also known as 7α-methyl-19-nortestosterone (MENT), is an experimental androgen/anabolic steroid (AAS) and progestogen medication which has been under development for potential use as a form of hormonal birth control for men and in androgen replacement therapy for low testosterone levels in men but has never been marketed for medical use.
[Uses]

Trestolone is a synthetic androgen used as a potential hormonal male contraceptive method that induces a state of termporary infertility.
[Mechanism of action]

Trestolone is a potent inhibitor of the release of the luteinizing hormone (LH) and follicle stimulating hormone (FSH). As spermatogenesis requires both testosterone and FSH, it is impaired by the reduction in FSH caused by trestolone as well as the reduction in LH, and subsequent reduction in testosterone.
[Side effects]

Side effects of trestolone include low estrogen levels and associated symptoms such as reduced sexual function and decreased bone mineral density among others.
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