| Identification | Back Directory | [Name]
Pro-xylane | [CAS]
439685-79-7 | [Synonyms]
bose for
Mexoryl SBB
Puri-Xylane
Tetrahydropyrantriol
Retinol Pro+Pro-xylane
Pro-Xylane,Puri-Xylane
Pro-xylane ISO 9001：2015 REACH
HYDROXYPROPYL TETRAHYDROPYRANTRIOL
Hydroxypropyl terrahydropy rantriol
Pro-xylane (Hydroxypropyl tetrahydropyrantriol)
L-gluco-Octitol, 1,5-anhydro-6,8-dideoxy-, (7ξ)-
Nano Liposomal HYDROXYPROPYL TETRAHYDROPYRANTRIOL
Nano liposomal hydroxypripyl tetrahydropyrantriol
(2S,3R,4S,5R)-2-(2-hydroxypropyl)oxane-3,4,5-triol | [EINECS(EC#)]
213-767-3 | [Molecular Formula]
C8H16O5 | [MDL Number]
MFCD32067869 | [MOL File]
439685-79-7.mol | [Molecular Weight]
192.21 |
| Questions And Answer | Back Directory | [cosmetic ingredient]
Pro-Xylane is a cosmetic ingredient used mainly as an anti-ageing agent in skin creams. Produced by Chimex, its chemical structure is derived from the xylose, a natural component of glycosaminoglycans and of hemicellulose. Pro-Xylane is produced in a two-steps process: 1) The reaction of xylose and acetylacetone in water, then 2) the hydrogenation of the intermediate. | [Physical Form]
Powder | [Cosmetics Application]
Pro-Xylane is a biochemical which induces neo-synthesis of matrix proteins. It is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. Pro-xylane is the first example of 'Green' chemical used in cosmetic.
Pro-Xylane is an ingredient originally developed by Lancome in 2006. According to research, it is a sugar-protein hybrid made from xylose, a sugar found abundantly in beech trees and known to stimulate the production of glycoaminoglycans (GAGs), molecules responsible for defending the skin against water loss. | [function]
Pro-Xylane is a sugar-molecule derived from the beech wood tree utilizing green chemistry. It functions, in vitro, by stimulating the production of proteoglycans, a water-absorbing molecule in human reconstructed skin. |
| Chemical Properties | Back Directory | [Boiling point ]
376.0±42.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [vapor pressure ]
0Pa at 25℃ | [storage temp. ]
Store at -20°C | [solubility ]
Water: 250 mg/mL (1300.66 mM); DMSO: ≥ 83.33 mg/mL (433.54 mM) | [pka]
13.55±0.70(Predicted) | [InChI]
InChI=1/C8H16O5/c1-4(9)2-6-8(12)7(11)5(10)3-13-6/h4-12H,2-3H2,1H3/t4?,5-,6+,7+,8+/s3 | [InChIKey]
KOGFZZYPPGQZFZ-ZXWVZLFTNA-N | [SMILES]
C([C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C(O)C |&1:1,4,6,8,r| | [LogP]
-2.07 |
| Hazard Information | Back Directory | [Description]
Pro-xylane (PX) is a cosmetic ingredient used for skin conditioning and is widely used in anti-aging product research. It is considered to be an optimal activator for the biosynthesis of glycosaminoglycans (GAGs) sulphate and can be used to prepare a novel bioactive c-glycoside compound, which is a "green" chemical. In addition, Pro-xylane has been shown to enhance the blue colour of anthocyanins (ACNs), with ACNs-PX showing a colour close to Oxford blue, a surface height of 2.13 ± 0.14 nm and a slight increase in stability[1-2]. | [Chemical Properties]
Pro-xylane is an organic compound with the appearance of a pale yellow to off-white powder or a colourless viscous liquid, stored in a cool dry place, and has been used in experiments related to the basic science of aging. | [Uses]
Pro-Xylane is a sugar-molecule derived from the beech wood tree utilizing green chemistry. It functions, in vitro, by stimulating the production of proteoglycans, a water-absorbing molecule in human reconstructed skin. Higher levels of proteoglycans within the reconstructed skin’s extracellular matrix correlate to increase skin-elasticity and firmness. In cosmetics, pro-xylane products are frequently incorporated into anti-aging lotions and creams to counterbalance signs of aging (i.e., fine lines and wrinkles). | [Mechanism of action]
Pro-Xylane enters the skin and stimulates the part that produces and builds the extracellular matrix (a gel-like network of proteins and sugars that act as a scaffold and shock absorber between cells) called proteoglycans.These molecules absorb water and make the matrix more gel-like, increasing the firmness of the cells and increasing the firmness of the skin.It can also serve as a highway to guide supplemental molecules (such as growing proteins) to cells.
| [References]
[1] ALEXANDRE CAVEZZA . Synthesis of Pro-XylaneTM: A new biologically active C-glycoside in aqueous media[J]. Bioorganic & Medicinal Chemistry Letters, 2009. DOI:10.1016/j.bmcl.2008.12.037.
[2] KAI DENG. Improved Stability of Blue Colour of Anthocyanins from Lycium ruthenicum Murr. Based on Copigmentation.[J]. Molecules, 2022. DOI:10.3390/molecules27186089.
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