| Identification | Back Directory | [Name]
4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE | [CAS]
479633-63-1 | [Synonyms]
Tofacitinib-9
Tofacitinib imurity
Tofacitinib Impurity R
Tofacitinib Impurity 53
Tofacitinib Impurity 20
4-Chloro-7-tosyl-7H-pyrro...
4-Chloro-7-tosyl-7H-pyrrolo[2
4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE
4-Chloro-7-(p-tolylsulfonyl)pyrrolo[2,3-d]pyrimidine
4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine
4-Chloro-7-(p-toluenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine
4-Chloro-7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidine
4-chloro-7-(4-methylphenyl)sulfonylpyrrolo[2,3-d]pyrimidine
4-Chloro-7-(p-toluenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine >
4-Chloro-7-[(4-methylbenzene)sulfonyl]pyrrolo[2,3-d]pyrimidine
4-CHLORO-7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDINE
4-Chloro-7-[(4-methylbenzene)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine
7H-Pyrrolo[2,3-D]pyriMidine,4-chloro-7-[(4-Methylphenyl)sulfonyl]-
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-2-yl) amino)piperidin-1-yl)-3-oxopropanenitrile | [EINECS(EC#)]
811-000-2 | [Molecular Formula]
C13H10ClN3O2S | [MDL Number]
MFCD09907939 | [MOL File]
479633-63-1.mol | [Molecular Weight]
307.76 |
| Chemical Properties | Back Directory | [Melting point ]
145.0 to 149.0 °C | [Boiling point ]
505.3±60.0 °C(Predicted) | [density ]
1.49 | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
powder to crystal | [pka]
1.73±0.30(Predicted) | [color ]
White to Orange to Green | [InChI]
InChI=1S/C13H10ClN3O2S/c1-9-2-4-10(5-3-9)20(18,19)17-7-6-11-12(14)15-8-16-13(11)17/h2-8H,1H3 | [InChIKey]
BTOJSYRZQZOMOK-UHFFFAOYSA-N | [SMILES]
C1=NC(Cl)=C2C=CN(S(C3=CC=C(C)C=C3)(=O)=O)C2=N1 |
| Hazard Information | Back Directory | [Uses]
4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine is a reagent in the synthesis of (+)-tofacitinib, a selective Janus kinase 3 inhibitor (JAK3) and an immunosuppressant drug. |
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