ChemicalBook--->CAS DataBase List--->533-70-0

533-70-0

533-70-0 Structure

533-70-0 Structure
IdentificationBack Directory
[Name]

2,4-Diiodoaniline
[CAS]

533-70-0
[Synonyms]

2,4-DIIODOANILINE
2,4-Diiodobenzene
(2,4-diiodophenyl)amine
[Molecular Formula]

C6H5I2N
[MDL Number]

MFCD01851096
[MOL File]

533-70-0.mol
[Molecular Weight]

344.92
Chemical PropertiesBack Directory
[Melting point ]

94-95°C
[Boiling point ]

346.0±32.0 °C(Predicted)
[density ]

2.7480
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[pka]

1.74±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Aniline-->Iodate(1-), dichloro-, potassium (9CI)-->Hydrochloric acid
Hazard InformationBack Directory
[Uses]

2,4-Diiodoaniline is an aromatic hydrocarbon derivative and is used as an intermediate in pharmaceutical synthesis. It is used to synthesis of 5-Iodo-2-phenyl-benzimidazole.
[Synthesis]

2,4-Diiodoaniline is generally prepared by the reactions of aniline with iodine in the presence of oxidants, with ICl vapor.
Step: Freshly distilled aniline (1mL, 11mmol) was dissolved in concentrated HCl (50 mL) and diluted with water to 0.5 L. Then KICl2 (5.2 g, 22 mmol) was added portionwise with vigorous stirring at ≈20 °C, this being followed by the gradual formation of a grayish precipitate. After completion of the reaction (3h), the precipitate was filtered off and recrystallized from benzene with addition of activated carbon. The yield of diiodoaniline was 2.14g (57%), m.p. 95 °C.
1H NMR (CDCl3), δ: 3.74 (br.s, 2 H, NH2); 6.49 (d, 1 H, C(6)H, J = 8.2 Hz); 7.36 (dd, 1 H, C(5)H, J1 = 1.0 Hz; J2 = 8.2 Hz); 7.87 (d, 1 H, C(3)H, J = 1 Hz).
533-70-0 suppliers list
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008657128800458; +8615858145714 , +8615858145714
Website: http://www.fandachem.com
Company Name: career henan chemical co
Tel: +86-0371-86658258
Website: https://www.coreychem.com/
Company Name: Wuhan Chemwish Technology Co., Ltd
Tel: 027-67849912
Website: www.chemicalbook.com/ShowSupplierProductsList485773/0.htm
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-029-81138252 +86-18789408387 , +86-18789408387
Website: https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-222/
Company Name: Antai Fine Chemical Technology Co.,Limited
Tel: 18503026267 , 18503026267
Website: www.chemicalbook.com/ShowSupplierProductsList1980510/0.htm
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 0551-65418671
Website: https://www.tnjchem.com
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250 , +86-15129568250
Website: https://www.dideu.com
Company Name: Finetech Industry Limited
Tel: +86-27-87465837 +8618971612321 , +8618971612321
Website: https://www.finetechnology-ind.com/
Company Name: Coresyn Pharmatech Co., Ltd.
Tel: +86-571-86626709 +86-18157142896 , +86-18157142896
Website: http://www.coresyn.com/
Company Name: Aromsyn Co., Ltd.
Tel: +86-0571-85585865 +8613336024896 , +8613336024896
Website: https://www.aromsyn.com/
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Website: http://www.amadischem.com
Company Name: Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel: +86-21-54098501
Website: www.sinch.com.cn
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Website: http://www.jkchemical.com
Company Name: Wuhan Chemwish Technology Co., Ltd  
Tel: 86-027-67849912
Website: www.chemwish.com
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 15221909166
Website: www.bidepharm.com
Company Name: Finetech Industry Limited  
Tel: 027-87465837 19945049750
Website: www.finetechchem.com/
Company Name: SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.  
Tel: 021-69106960 13701823733
Website: www.bangchengchem.com/
Company Name: Nanjing Chalf-Pharm Technology Co., Ltd.  
Tel: 025-57018978 18251899859
Website: http://www.chalf-pharm.com
Tags:533-70-0 Related Product Information
121-69-7 99-98-9 122-39-4 62-53-3 578-54-1 91-68-9 6152-67-6 540-37-4 35453-19-1 3119-15-1 737-31-5 609-86-9 31112-62-6 66108-95-0 85-36-9 96-83-3 37441-29-5