| Identification | Back Directory | [Name]
Platycodin D2 | [CAS]
66663-90-9 | [Synonyms]
Platycodin D2
Olean-12-en-28-oic acid, 3-[(3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,16,23,24-tetrahydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,16α)- | [Molecular Formula]
C63H102O33 | [MDL Number]
MFCD29904544 | [MOL File]
66663-90-9.mol | [Molecular Weight]
1387.46 |
| Chemical Properties | Back Directory | [density ]
1.60±0.1 g/cm3 (20 ºC 760 Torr) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
12.70±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalacin D2 has anti-cancer activity, it exhibits significant inhibition on the proliferation of five kinds of cultured human tumor cell lines. | [Definition]
ChEBI: Platycodin D2 is a triterpenoid saponin. It has a role as a metabolite. | [Biological Activity]
Platycodin D2 is a saponin isolated from Platycodon grandiflorum, with anti-cancer activity. | [in vitro]
A novel triterpenoid saponin, deapioplatycoside Ewas isolated from the root extract of Platycodon grandiflorum, together with the seven known saponins 2 - 8, i. e., platycoside E, deapioplatycodin D3 , platycodin D3, polygalacin D2, Platycodin D2 , deapioplatycodin D and platycodin D. The structure of the new saponin 1 was determined on the basis of spectral analysis and chemical evidence. | [target]
IFN-γ | IL Receptor | HBV |
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