ChemicalBook--->CAS DataBase List--->67452-97-5

67452-97-5

67452-97-5 Structure

67452-97-5 Structure
IdentificationBack Directory
[Name]

Alclometasone
[CAS]

67452-97-5
[Synonyms]

Vaderm
Alclometasone
AlcloMethasone
ALCLOMETHASONE DIPROPIONATE
7α-Chloro-16α-methylprednisolone
7α-Chloro-16α-methyl Prednisolone
7α-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
(7α,11β,16α)-7-Chloro-11,17,21-trihydroxy-16-Methylpregna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione, 7-chloro-11,17,21-trihydroxy-16-methyl-, (7α,11β,16α)-
[Molecular Formula]

C22H29ClO5
[MOL File]

67452-97-5.mol
[Molecular Weight]

408.92
Chemical PropertiesBack Directory
[Melting point ]

176-179°
[alpha ]

D26 +47.5° (c = 0.3 in DMF)
[Boiling point ]

607.1±55.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

12.30±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

A metabolite of Alclometasone dipropionate (A514580); a synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasocons trictive agent.
[Uses]

As a metabolite of Alclometasone dipropionate; Alclometasone can be used as a synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
[Definition]

ChEBI: A prednisolone compound having an alpha-chloro substituent at the 7-position and an alpha-methyl substituent at the 16-position.
[Brand name]

Aclovate (GlaxoSmithKline).
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