| Identification | Back Directory | [Name]
CAFTARIC ACID | [CAS]
67879-58-7 | [Synonyms]
Caftaricaci
CAFTARIC ACID
Cafftaric acid
trans-Caftaric acid
CAFTARIC ACID USP/EP/BP
trans-Caffeoyl tartrate
(2R,3R)-(-)-CAFTARIC ACID)
2-Caffeoyl-L-tartaric acid
Caftaric acid (trans-Caftaric acid)
MONO-(3,4-DIHYDROXYCINNAMOYL)-TARTARIC ACID
(2R,3R)-2-[(3,4-Dihydroxy-trans-cinnamoyl)oxy]-3-hydroxybutanedioic acid
(2R,3R)-2-(((E)-3-(3,4-Dihydroxyphenyl)acryloyl)oxy)-3-hydroxysuccinic acid
(2E,3R)-2-[[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL)OXY]-3-HYDROXYBUTANEDIOIC ACID
(2R,3R)-2-[[(E)-1-Oxo-3-(3,4-dihydroxyphenyl)-2-propenyl]oxy]-3-hydroxybutanedioic acid
(2R,3R)-2-[[(E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3-hydroxybutanedioic acid
Butanedioic acid, 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3-hydroxy-, (2R,3R)- | [Molecular Formula]
C13H12O9 | [MDL Number]
MFCD02094177 | [MOL File]
67879-58-7.mol | [Molecular Weight]
312.23 |
| Chemical Properties | Back Directory | [Melting point ]
124～125℃ | [Boiling point ]
618.2±55.0 °C(Predicted) | [density ]
1.694±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Methanol (Slightly), Water (Slightly, Heated, Sonicated) | [form ]
neat | [pka]
2.18±0.25(Predicted) | [color ]
White to Pale Beige | [Odor]
at 100.00?%. odorless | [Stability:]
Hygroscopic | [LogP]
1.147 (est) |
| Hazard Information | Back Directory | [Description]
Caftaric acid is a phenolic acid and a tartaric acid ester form of caffeic acid (Item No. 70602).1 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) free radicals in a cell-free assay (EC50 = 20.4 μM) and inhibits oxidation of LDL isolated from human plasma by 97.6% compared to vehicle control in vitro when used at a concentration of 5 μM.2,3 Caftaric acid is the main phenolic compound in V. vinifera white, pink, and black table grapes as well as various wines.4 In vivo, caftaric acid content in dietary-administered red wine positively correlates with inhibition of protein carbonylation and decreased superoxide dismutase (SOD), glutathione peroxidase (Gpx), and catalase activities in mice.5 | [Uses]
Caftaric Acid is used in cancer therapy as an anticancer drug. Affecting the up regulation or down regulation of drug transporters or cytochrome p450 enzymes. Also provides antioxidant effects, found in wines. | [Definition]
ChEBI: Caftaric acid is a hydroxycinnamic acid. | [target]
LDL | NO |
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