ChemicalBook--->CAS DataBase List--->90693-88-2

90693-88-2

90693-88-2 Structure

90693-88-2 Structure
IdentificationBack Directory
[Name]

1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)
[CAS]

90693-88-2
[Synonyms]

18:1 PS (DOPS)
1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (SODIUM SALT);18:1 PS (DOPS)
[Molecular Formula]

C42H78NO10P.Na
[MOL File]

90693-88-2.mol
[Molecular Weight]

811.03
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Chloroform: 10 mg/ml
[form ]

A crystalline solid
[InChIKey]

RRLDZFIFYLDDLI-OLZOWLLTNA-N
[SMILES]

[C@H](COC(=O)CCCCCCC/C=C\CCCCCCCC)(OC(=O)CCCCCCC/C=C\CCCCCCCC)COP(O)(=O)OC[C@H](N)C(=O)O.[NaH] |&1:0,49,r|
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

1,2-Dioleoyl-sn-glycero-3-PS (DOPS) is a phospholipid containing oleic acid (Item Nos. 90260 | 24659) at the sn-1 and sn-2 positions, respectively. Nanovesicles composed of DOPS and the lysosomal protein saposin C (SapC) are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model. DOPS has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.
[Uses]

1,?2-?Dioleoyl-?sn-?glycero-?3-?phospho-?L-?serine Sodium Salt is a lipid being studied in the assembly and long-term stability of solid supported lipid bilayers from artificial and natural lipid mixtures.
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