104180-23-6
中文名称
ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-VAL-ILE-HIS-ASN
CAS
104180-23-6
分子式
C83H122N24O19
分子量
1760.01
MOL 文件
104180-23-6.mol
更新日期
2024/05/05 20:58:34
104180-23-6 结构式
基本信息
中文别名
人ANGIOTENSINOGEN (1-14)肽 英文别名
DRVYIHPFHLVIHNRENIN SUBSTRATE
ANGIOTENSINOGEN
Tetradecapeptid
H-DRVYIHPFHLVIHN-OH
ANGIOTENSINOGEN 1-14
ANGIOTENSIN PRECURSOR
RENIN SUBSTRATE, HUMAN
PREANGIOTENSINOGEN 1-14
HUMAN PREANGIOTENSINOGEN 1-14
常见问题列表
生物活性
Angiotensinogen (1-14), human 是肾素底物血管紧张素原 (angiotensinogen) 的片段,血管紧张素原是天然存在的肾素底物,也是所有血管紧张素肽的前体。靶点
Human Endogenous Metabolite
|
体外研究
Angiotensinogen (AGT) is the only precursor of all angiotensin peptides. Human AGT has 485 amino acids, including a 33 amino-acid signal peptide. The 10 N-terminal amino acids are cleaved by renin to provide angiotensin I (AngI), which is the source for an array of active angiotensin peptides.
Angiotensinogen isolated from most species is cleaved by human renin. Synthetic peptides containing the N-terminal amino-acid sequence of angiotensinogen were renin substrates.