111-57-9
中文名称
硬脂酰胺 MEA
英文名称
STEAROYL ETHANOLAMIDE
CAS
111-57-9
分子式
C20H41NO2
分子量
327.55
MOL 文件
111-57-9.mol
更新日期
2024/05/10 10:27:27
111-57-9 结构式
基本信息
中文别名
十八酰胺乙醇硬脂酰胺 MEA
硬脂酸单乙醇酰胺
N-(2-羟基乙基)硬脂酰胺
N-(2-羟基乙基)十八烷酰胺
英文别名
SEAAM-1105
CERAMID
STEARAMIDE MEA
STEAROYL ETHANOLAMIDE
N-Stearoylethanolamide
stearic monoethanolamide
Stearyl monoethanolamide
STEARIC ACID ETHANOLAMIDE
Stearoylethanolamide(SEA)
所属类别
化学试剂：酰胺物理化学性质
熔点103-104 °C(Solv: ethanol (64-17-5))
沸点486.0±28.0 °C(Predicted)
密度0.904±0.06 g/cm3(Predicted)
蒸气压0Pa at 20℃
储存条件−20°C
溶解度DMF: >2 mg/ml; DMSO: >100 μg/ml; Ethanol: >2 mg/ml; PBS pH 7.2: >100 μg/ml
酸度系数(pKa)14.49±0.10(Predicted)
形态crystalline
水溶解性1mg/L at 20℃
InChIInChI=1S/C20H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h22H,2-19H2,1H3,(H,21,23)
InChIKeyOTGQIQQTPXJQRG-UHFFFAOYSA-N
SMILESC(NCCO)(=O)CCCCCCCCCCCCCCCCC
LogP4.46 at 20℃
常见问题列表
生物活性
Stearoylethanolamide 是一种具有促细胞凋亡活性的内源性大麻素类化合物。靶点
|
Human Endogenous Metabolite
|
体外研究
Stearoylethanolamide (SEA) is present in human, rat and mouse brain in amounts comparable with those of the endocannabinoid anandamide (arachidonoylethanolamide; AEA). Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity, which is regulated by NO in a way opposite to that reported for AEA.