1620278-72-9
中文名称
TLR7/8激动剂1二盐酸盐
英文名称
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
CAS
1620278-72-9
分子式
C22H26ClN5
分子量
395.94
MOL 文件
1620278-72-9.mol
更新日期
2024/05/30 16:02:16
1620278-72-9 结构式
基本信息
中文别名
二盐酸TLR7/8 AGONIST 11-(4-(氨基甲基)苄基)-2-丁基-1H-咪唑并[4,5-C]喹啉-4-胺二盐酸盐
英文别名
TLR7/8 agonist-5d8 agonist 1 dihydrochloride
TLR7/8 Agonist 1 (hydrochloride)
TLR7/8 agonist 1 (dihydrochloride)
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
所属类别
生物化工：生化试剂常见问题列表
生物活性
TLR7/8 agonist 1 dihydrochloride 是一种 toll 样受体 TLR7/TLR8 的双重激动剂。靶点
TLR7/TLR8
体外研究
TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.