1881233-39-1
1881233-39-1 结构式
基本信息
PI4KIII beta inhibitor 1
N-(5-(3-(N-(4-HYDROXYPHENYL)SULFAMOYL)-4-METHOXYPHENYL)-4-METHYLTHIAZOL-2-YL)PIVALAMIDE
N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Propanamide, N-[5-[3-[[(4-hydroxyphenyl)amino]sulfonyl]-4-methoxyphenyl]-4-methyl-2-thiazolyl]-2,2-dimethyl-
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-100198 | 1881233-39-1 PI4KIIIbeta-IN-10 | 1881233-39-1 | 1mg | 1300元 |
| 2024/04/30 | HY-100198 | 1881233-39-1 PI4KIIIbeta-IN-10 | 1881233-39-1 | 5mg | 2900元 |
| 2024/04/30 | HY-100198 | 1881233-39-1 PI4KIIIbeta-IN-10 | 1881233-39-1 | 10mM * 1mLin DMSO | 3034元 |
常见问题列表
|
PI4KIIIβ 3.6 nM (IC 50 ) |
PI4KIIIα 3 μM (IC 50 ) |
PI3Kδ 720 nM (IC 50 ) |
PI3KC2γ 1 μM (IC 50 ) |
PI3Kα 10 μM (IC 50 ) |
PI3Kγ 20 μM (IC 50 ) |
PI4KIIIbeta-IN-10 (Compound 10) is a potent PI4KIIIβ inhibitor with very minor off-target inhibition of PI4KIIIβ related lipid kinases. PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2γ (IC 50 ~1 µM), PI3Kα (~10 µM), and PI4KIIIα (~3 µM), and <20% inhibition at concentrations up to 20 µM for PI4K2α, PI4K2β, and PI3Kβ.