2179-37-5
2179-37-5 结构式
基本信息
中文别名
哈里多苄环烷
平痉可宁
苄环庚烷
胺苄环已醚
英文别名
Benzcyclanbencyclane
Benzcyclane
3-[1-(benzyl)cycloheptoxy]propyl-dimethyl-amine
N,N-dimethyl-3-[1-(phenylmethyl)cycloheptyl]oxypropan-1-amine
N,N-dimethyl-3-[1-(phenylmethyl)cycloheptyl]oxy-propan-1-amine
1-Propanamine, N,N-dimethyl-3-[[1-(phenylmethyl)cycloheptyl]oxy]-
物理化学性质
沸点bp3 146-156°
密度0.97±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)pKa 8.94±0.04(40%EtOH t=25.0) (Uncertain)
常见问题列表
生物活性
Benzcyclane (Bencyclane) 是血小板聚集抑制剂和有效研究各种外周循环障碍的血管扩张剂。体内研究
Benzcyclane, although capable of aggregating platelets by itself at very high concentrations, shows a striking inhibitory effect, over a wide range of concentrations, both on platelet aggregation induced by ADP, epinephrine or collagen and on platelet adhesiveness to glass or collagen. Clot retraction is also clearly inhibited. Benzcyclane induces use-dependent inhibition of Na channels in muscle, similarly as do class 1 antiarrhytnmic drugs. Inhibition was observed with both normal and cevadine-modified Na channels.