2601-90-3
2601-90-3 结构式
基本信息
英文别名
OleoylglycineN-OLEOYLGLYCINE
N-Oleoylglycine >=98%
N-(9Z-OCTADECENOYL)-GLYCINE
N-[(Z)-1-Oxo-9-octadecenyl]glycine
(Z)-N-(1-oxo-9-octadecenyl)glycine
N-(1-OXO-9-OCTADECENYL)-(Z)-GLYCINE
Glycine, N-[(9Z)-1-oxo-9-octadecen-1-yl]-
物理化学性质
熔点77-78 °C
沸点525.6±43.0 °C(Predicted)
密度0.962±0.06 g/cm3(Predicted)
储存条件−20°C
酸度系数(pKa)3.59±0.10(Predicted)
常见问题列表
生物活性
N-Oleoyl glycine 是一种脂氨酸，在 3T3-L1 脂肪细胞中，能够通过激活 CB1 受体和 Akt 信号通路来刺激脂肪形成。靶点
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Human Endogenous Metabolite
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CB1
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Akt
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体外研究
N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. N-Oleoyl glycine (1, 5, 10, 20, 50 μM) dose- and time-dependently stimulates 3T3-L1 adipogenesis after treatment for 1-10 days via activation of CB1R. N-Oleoyl glycine also elevates Akt signaling pathway during the differentiation of 3T3-L1 adipocytes.