291758-32-2
中文名称
NΩ-羟基或- L -精氨酸盐酸盐
英文名称
N-OMEGA-HYDROXYL-NOR-L-ARGININE, DIHYDROCHLORIDE
CAS
291758-32-2
分子式
C5H12N4O3
分子量
176.174
MOL 文件
291758-32-2.mol
更新日期
2024/05/28 11:40:31
291758-32-2 结构式
基本信息
中文别名
NΩ-羟基或- L -精氨酸盐酸盐(S)-2-氨基-4-(3-羟基胍基)丁酸二盐酸盐
英文别名
nor-NOHA HClNω-Hydroxy-nor-L-Arginine Dihydrochloride
N-OMEGA-HYDROXYL-NOR-L-ARGININE, DIHYDROCHLORIDE
(2S)-2-AMino-4-[[(hydroxyaMino)iMinoMethyl]aMino]butanoic Acid
(S)-2-Amino-4-(3-hydroxyguanidino)butanoic acid dihydrochloride
应用领域
用途一
Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a reversible, competitive inhibitor of arginase. It is neither a substrate nor an inhibitor for iNOS and it appears as a useful tool to study the interplays between arginase and NOS. Was found to be much more potent than NOHA and homo-NOHA to inhibit the rat liver arginase-dependent hydrolysis of L-arg.