303-97-9
303-97-9 结构式
基本信息
泛醌-9
泛醌-45
辅酶Q10杂质
辅酶Q9(标准品)
癸利酮杂质1(辅酶Q9)
CoQ9
coq(sub9)
NSC 226993
COENZYME Q9
UBIQUINONE-9
UBIQUINONE-45
Ubiquinone Q9
coenzymeq(sub9)
Q-9,Ubiquinone-9
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-101415 | 辅酶Q9 Coenzyme Q9 | 303-97-9 | 5mg | 860元 |
| 2024/04/30 | XW30397901 | 辅酶Q9 | 303-97-9 | 5MG | 941元 |
| 2024/01/25 | HY-101415 | 辅酶Q9 Coenzyme Q9 | 303-97-9 | 1mg | 550元 |
常见问题列表
|
Human Endogenous Metabolite
|
Coenzyme Q9 (5 mg/kg; p.o.; once a day for 4 weeks) reduces myocardial ischemia/reperfusion injury.
CoQ
10
and CoQ
9
are components of themitochondrial respiratory chain in mammals and can regulate some mitochondrial proteins/functions. Soybean, corn, and rapeseed oils are very rich sources of CoQ
10
, whereas CoQ
9
has been found in high concentrations in corn oil.
The lack of a functional CoQ
9
protein in homozygous CoQ
9
mutant (CoQ
9
(X/X)) mice causes a severe reduction in the CoQ
7
protein and a widespread CoQ deficiency and accumulation of demethoxyubiquinone. The deficit in CoQ induces a brain-specific impairment of mitochondrial bioenergetics performance, a reduction in respiratory control ratio, ATP levels and ATP/ADP ratio and specific loss of respiratory complex I. These effects lead to neuronal death and demyelinization with severe vacuolization and astrogliosis in the brain of CoQ
9
(X/X) mice that consequently die between 3 and 6 months of age.
| Animal Model: | Male Hartley guinea pigs of about 350-400 g body weight |
| Dosage: | 5 mg/kg of body weight |
| Administration: | P.o.; once a day for 4 weeks |
| Result: | Nutritional supplementation of CoQ9 can reduce myocardial ischemia/reperfusion injury to the same extent as CoQ10. |