469-21-6
中文名称
多西拉敏
英文名称
DOXYLAMINE
CAS
469-21-6
分子式
C17H22N2O
分子量
270.37
MOL 文件
469-21-6.mol
更新日期
2023/06/13 13:17:10
469-21-6 结构式
基本信息
中文别名
多西拉敏多沙胺杂质
英文别名
oxylamineDOXYLAMINE
NCI C60684
DOXYLAMINE USP/EP/BP
Doxylamine Hydrogen inate
2-dimethylaminoethoxyphenylmethyl-2-picoline
alpha-Dimethylaminoethoxyphenylmethyl-2-picoline
2-[a-(2-dimethylaminoethoxy)-a-methylbenzyl]pyridine
dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine
phenyl-2-pyridylmethyl-b-N,N-dimethylaminoethyl ether
所属类别
原料药：抗组胺药物理化学性质
熔点25°C
沸点bp0.5 137-141°
密度1.0023 (rough estimate)
折射率1.5486 (estimate)
储存条件-20°C Freezer, Under inert atmosphere
溶解度乙腈（微溶）、氯仿（微溶）、甲醇（微溶）
酸度系数(pKa)pKa 9.20(H2O
t = 25
c = 0.002–0.01) (Uncertain);4.4 (Uncertain);9.2 (Uncertain)
形态Oil
颜色无色
稳定性对温度敏感
EPA化学物质信息Doxylamine (469-21-6)
安全数据
警示词警告
危险性描述H302-H315-H319-H335
毒性An antihistamine
that formerly was used in pregnant women for antihistaminic
and sedative properties. Although it has excellent
sedative properties, it has been implicated in teratogenesis and
in causing neurobehavioral toxicity and is therefore no longer
used