64019-93-8
中文名称
盐酸地匹福林
英文名称
Dipivefrin hydrochloride
CAS
64019-93-8
分子式
C19H30ClNO5
分子量
387.898
MOL 文件
64019-93-8.mol
更新日期
2024/03/22 17:31:02
64019-93-8 结构式
基本信息
中文别名
盐酸地匹福林盐酸二维弗林
盐酸地哌夫林
5-羟基色氨酸对照品
盐酸地匹福林 EP标准品
盐酸地匹福林 [64019-93-8]
4-(1-羟基-2-(甲基氨基)乙基)-1,2-苯二醇二特戊酸酯盐酸盐
英文别名
ProgateDiopine
Pivalephrine
Dipivefrine HCL
hydrochloride,(+-)-este
dipivefrinhydrochloride
dipivefrinehydrochloride
Dipivefrine hydrochloride CRS
dipivalylepinephrinehydrochloride
DIPIVEFRIN HYDROCHLORIDE (200 MG)
所属类别
原料药：眼科用药物理化学性质
熔点158-159°
储存条件Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度Freely soluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent) and in methylene chloride.
酸度系数(pKa)8.40(at 25℃)
形态neat
颜色白色至灰白色
常见问题列表
生物活性
Dipivefrin hydrochloride (Dipivefrine hydrochloride) 是一种抗青光眼前体药物，通过角膜中的酯酶水解为其活性化合物肾上腺素。体内研究
Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms.
| Animal Model: | Male 60-day-old CFW mice (23-28 g) |
| Dosage: | 0.3 μg/kg, 1.0 μg/kg, 3.0 μg/kg, 10 μg/kg |
| Administration: | Intraperitoneal injection; post-training |
| Result: | Significantly enhanced retention of both inhibitory avoidance and Y-maze discrimination tasks in a dose-dependent manner. |