64790-15-4
64790-15-4 结构式
基本信息
glucagon(19-29
GLUCAGON (19-29), HUMAN
Miniglucagon (huMan, rat, porcine)
Glucagon (19-29) (human, rat, porcine)
GLUCAGON (19-29), BOVINE, HUMAN, PORCINE
GLUCAGON (19-29) (HUMAN, BOVINE, PORCINE)
PHE-VAL-GLN-TRP-LEU-MET-ASN-THR: FVQWLMNT
ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR
H-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR-OH
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-P0150 | ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR Glucagon (19-29), human | 64790-15-4 | 5mg | 420元 |
| 2024/04/30 | HY-P0150 | ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR Glucagon (19-29), human | 64790-15-4 | 10mg | 600元 |
| 2024/04/30 | HY-P0150 | ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR Glucagon (19-29), human | 64790-15-4 | 25mg | 950元 |
常见问题列表
Insulin secretion
Glucagon (19-29), from 0.1 pM to 1 nM, exerts a potent negative inotropic action. The most striking observation is a 45% increase in the amplitude of cell contractility elicited by the combination of 30 nM glucagon with 1 nM Glucagon (19-29).
Glucagon (19-29), also named Miniglucagon, is the COOH-terminal (19-29) fragment processed from glucagon. Glucagon (19-29) dose-dependently inhibits insulin secretion stimulated by 8.3 M glucose, with no change in the perfusion flow rate. A concentration of 1 nM Glucagon (19-29) has a significant inhibitory effect on a 1 nM glucagon-like peptide 1 (7-36) amide–potentiated insulin secretion. Glucagon (19-29) is a highly potent and efficient inhibitor of insulin release by closing, via hyperpolarization, voltage-dependent Ca 2+ channels linked to a pathway involving a pertussis toxin-sensitive G protein.