68483-33-0

中文名称 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate

英文名称 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate

CAS 68483-33-0

分子式 C27H23ClN2O5

分子量 490.93

MOL 文件 68483-33-0.mol

68483-33-0 结构式

基本信息物理化学性质图谱信息 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate价格(试剂级) 常见问题列表

基本信息

中文别名

化合物 T10355
化合物APYRAMIDE

英文别名

apyramide
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester
1-(4-Chlorobenzoyl)-2-methyl-5-methoxy-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(acetylamino)phenyl ester

物理化学性质

熔点145-150 °C(Solv: benzene (71-43-2); methanol (67-56-1))

沸点671.1±55.0 °C(Predicted)

密度1.29±0.1 g/cm3(Predicted)

储存条件-20°C储存

溶解度溶于二甲基亚砜

酸度系数(pKa)14.20±0.70(Predicted)

图谱信息

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate(68483-33-0)核磁图(¹HNMR)

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate价格(试剂级)

报价日期	产品编号	产品名称	CAS号	包装	价格
2024/04/30	HY-U00046	4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide	68483-33-0	5mg	2000元
2024/04/30	HY-U00046	4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide	68483-33-0	10mg	3400元
2024/04/30	HY-U00046	4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide	68483-33-0	20mg	6000元

常见问题列表

生物活性

Apyramide 是一种抗炎试剂 (NSAID)，是吲哚美辛 (HY-14397) 的前药。Indomethacin 是一种强效的、血脑通透的、非选择性的 COX1 和 COX2 抑制剂。

体内研究

Apyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities.