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68813-55-8

中文名称 酚嘧啶 扑蛲灵
英文名称 OXANTEL PAMOATE
CAS 68813-55-8
分子式 C49H48N4O8
分子量 820.93
MOL 文件 68813-55-8.mol
更新日期 2023/03/20 15:41:17
68813-55-8 结构式 68813-55-8 结构式

基本信息

中文别名
奥克太
酚嘧啶
酚嘧啶 扑蛲灵
含 4,4′-亚甲基双(3-羟基-2-萘甲酸) 的 1-甲基-2-(3-羟基苯乙烯基)-1,4,5,6-四氢嘧啶化合物
英文别名
OXANTEL PAMOATE
Oxantel Ebonate
Einecs 272-332-6
Octahydronaphthol
Parasite,inhibit,Inhibitor,Oxantel Pamoate,Oxantel
1-METHYL-2-[3-HYDROXYPHENYLETHENYL]-1,4,5,6-TETRAHYDROPYRIMIDINE COMPOUND WITH 4,4'-METHYLENEBIS[3-HYDROXY-2-NAPHTHOIC ACID]
1-methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid)
4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid 3-[(1E)-2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol
(E)-3-[2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylate] Salt
4,4'-methylenebis[3-hydroxy-2-naphthoic] acid, compound with (E)-3-[2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl]phenol (1:1)
所属类别
分析化学:法医和兽医标准品

物理化学性质

熔点>224°C (dec.)
储存条件Amber Vial, Refrigerator, Under inert atmosphere
溶解度可溶于DMSO(略微加热)、甲醇(略微加热)
形态neat
颜色白色至灰白色
InChIKeyWSYDAPQDBDVYIO-QEFJDTIGSA-N

安全数据

危险性符号(GHS)
GHS07
警示词警告
危险性描述H302-H315-H319-H335
WGK Germany3
酚嘧啶 扑蛲灵价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/04/30HY-B1344酚嘧啶 扑蛲灵
Oxantel pamoate
68813-55-810mM * 1mLin DMSO220元
2024/04/30S5722酚嘧啶 扑蛲灵
Oxantel Pamoate
68813-55-825mg795.36元
2024/01/25HY-B1344酚嘧啶 扑蛲灵
Oxantel pamoate
68813-55-8100mg600元

常见问题列表

生物活性
Oxantel pamoate 是一种广泛使用的驱虫剂,有效针对Trichuris muris 和钩虫。
靶点

Antiparasitic

体内研究

The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris , Ancylostoma ceylanicum and Necator americanus . An ED 50 s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED 50 s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris -infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus .

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