69304-47-8
69304-47-8 结构式
基本信息
溴夫啶
溴夫定
布里夫定
溴比夫定
布瑞夫定
溴乙烯尿苷
溴夫定/溴夫啶
溴夫定(标准品)
(E)-5-(2-溴乙烯基)-2'-脱氧核苷
BVDR
BrVDU
Helpin
Brivudin
SC-38394
BRIVUDINE
Brivudine BVdU
Brivudine USP/EP/BP
Bromovinyldeoxyuridine
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | H27853 | (E)-5-(2-溴乙烯基)-2'-脱氧核苷, 98% (E)-5-(2-Bromovinyl)-2'-deoxyuridine, 98% | 69304-47-8 | 50mg | 793元 |
| 2024/04/30 | H27853 | (E)-5-(2-溴乙烯基)-2'-脱氧核苷, 98% (E)-5-(2-Bromovinyl)-2'-deoxyuridine, 98% | 69304-47-8 | 250mg | 2439元 |
| 2024/04/30 | H27853 | (E)-5-(2-溴乙烯基)-2'-脱氧核苷, 98% (E)-5-(2-Bromovinyl)-2'-deoxyuridine, 98% | 69304-47-8 | 1g | 6302元 |
常见问题列表
Brivudine is an analog of thymidine, and is incorporated into the viral DNA. It blocks the action of DNA polymerases, thus inhibiting viral replication. It has a stronger antiviral effect against the varicella-zoster virus compared with reference compounds such as aciclovir or penciclovir. It has high, selective activity against varicella zoster virus (VZV), inhibiting VZV replication, possibly through competitive inhibition of viral DNA polymerase, or by acting as an alternative substrate to deoxythymidine triphosphate, causing viral DNA strand breakage.
At a dose of 125 mg once daily, brivudine has proved to be superior to aciclovir with respect to reducing the period of new blister production, and has shortened the duration of post-herpetic neuralgia.