802918-35-0
中文名称
西那卡塞杂质18
英文名称
(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
CAS
802918-35-0
分子式
C22H24F3N
分子量
359.428
MOL 文件
802918-35-0.mol
802918-35-0 结构式
基本信息
中文别名
西那卡塞杂质18西那卡塞杂质15(单体)
西那卡塞杂质 CINACALCET
英文别名
"(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)(R)-1-(phthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethan-1-aminehydrochloride
(R)-1-(naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethan-1-aminehydrochloride
(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
1-(7,8-Dihydro-napthalen-1-yl)-ethyl]- [3-(3-trifluoromethyl-phenyl)]-amine hydrochloride
(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine
(E)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide hydrochloride
所属类别
分析化学：药典标准品和杂质标准品应用领域
用途一
(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455335) using HPLC.