85-87-0
85-87-0 结构式
基本信息
吡多胺
Pyridorin
PyridoxaMine-d4
pyridoxamine USP/EP/BP
4-(aminomethyl)-2-methyl-5-methylol-pyridin-3-ol
4-Aminomethyl-5-hydroxy-6-methyl-3-pyridinemethanol
3-Pyridinemethanol, 4-(aminomethyl)-5-hydroxy-6-methyl-
4-(aminomethyl)-5-(hydroxymethyl)-2-methyl-pyridin-3-ol
3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinemethanamine
4-(azaniumylmethyl)-5-(hydroxymethyl)-2-methylpyridin-3-olate
物理化学性质
常见问题列表
维生素B6（Vitamin B6）又称吡哆素，其包括吡哆醇、吡哆醛及吡哆胺，在体内以磷酸酯的形式存在，是一种水溶性维生素，遇光或碱易破坏，不耐高温。1936年定名为维生素B6。维生素B6为无色晶体，易溶于水及乙醇，在酸液中稳定，在碱液中易破坏，吡哆醇耐热，吡哆醛和吡哆胺不耐高温。
维生素B6的基本结构是2-甲基-3-羟基-5-羟甲基吡啶包括三种形式: 吡哆醇(PN)、吡哆醛(PL)和吡哆胺(PM),均具有维生素B6的生物活性,这三种形式在体内可以相互转变,动物组织内多以吡哆醛及吡哆胺存在,植物中则以吡哆醇为多。维生素B6易溶于水，对酸相当稳定，在碱性溶液中易破坏，在中性溶液中易被光破坏,对氧较稳定。吡哆醛和吡哆胺较不耐热,吡哆 醇耐热,在食品加工、储存过程中稳定性好。
植物中的维生素以吡哆醇形式存在，动物产品含有吡哆胺和吡哆醛。吡哆醇及其衍生物广泛分布于酵母、谷类、肝脏和乳中。
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Human Endogenous Metabolite
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Pyridoxylamine (PM), a member of the B 6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.
Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo.