86445-22-9
中文名称
Auxinole
英文名称
Auxinole
CAS
86445-22-9
分子式
C20H19NO3
分子量
321.37
MOL 文件
86445-22-9.mol
更新日期
2024/04/15 22:10:26
86445-22-9 结构式
常见问题列表
生物活性
Auxinole 是一种有效的 TIR1/AFB 受体植物激素拮抗剂，能够与 TIR1 结合，阻止 TIR1-IAA-Aux/IAA 复合物的形成，从而抑制 auxin 应答基因的表达。靶点
TIR1/AFB receptor
体外研究
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, and binds TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and then inhibits auxin-responsive gene expression. In addition, Auxinole competitively inhibits various auxin responses in planta. Auxinole causes reduction in IAA-triggered depolarization in root hair cells. Auxinole (20 µM) also represses the transient increase in [Ca 2+ ] cyt completely, and blocks Ca 2+ response.