137213-91-3
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- CAS号:
- 137213-91-3
- 英文名:
- (4-acetamidocyclohexyl) nitrate
- 英文别名:
- (4-acetamidocyclohexyl) nitrate;Acetamide, N-[trans-4-(nitrooxy)cyclohexyl]-;(4Acetamidocyclohexyl) nitrate,(4 Acetamidocyclohexyl) nitrate
- 中文名:
- 137213-91-3
- 中文别名:
- 化合物 T10562
- CBNumber:
- CB01871449
- 分子式:
- C8H14N2O4
- 分子量:
- 202.21
- MOL File:
- 137213-91-3.mol
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137213-91-3化学性质
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沸点:
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378.8±22.0 °C(Predicted)
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密度:
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1.20±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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15.48±0.40(Predicted)
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137213-91-3性质、用途与生产工艺
(4-Acetamidocyclohexyl) nitrate (BM121307) 是一种鸟苷酸环化酶 (guanylate cyclase) 激活剂。
The elimination of BM121307 and its metabolites via urine and feces amount to 76.5% after oral application, and to 80.7% of the applied dose after intravenous application. The major amount of radioactivity is eliminated via urine (69.4% and 73.6% of the dose, respectively), whereas the fecal elimination is found to be negligible. Investigations of the urinary samples show that the drug is metabolized to a high percentage trans-N-(4-Hydroxycyclohexyl) acetamide is the main metabolite; 73% of the radioactive compounds (after p.o.-administration and 69% after intravenous application could be identified as the alcohol of BM121307; the amounts of the drug totaled 9% and 13%, respectively.
137213-91-3
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137213-91-3, 137213-91-3 相关搜索:
- 化合物 T10562
- 137213-91-3
- (4Acetamidocyclohexyl) nitrate,(4 Acetamidocyclohexyl) nitrate
- Acetamide, N-[trans-4-(nitrooxy)cyclohexyl]-
- (4-acetamidocyclohexyl) nitrate