卡普瑞林酒石酸盐
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- CAS号:
- 193273-69-7
- 英文名:
- CaproMorelin Tartrate
- 英文别名:
- CS-2136;CP 424391-18;CP-424391 tartrate;CaproMorelin Tartrate;CP 424391-18; CP-424391 TARTRATE;Capromorelin tartrate (CP-424,391);Inhibitor,Growth hormone secretagogue receptor,GHSR,Capromorelin,inhibit,Capromorelin Tartrate;N-{2-[(3aS)-3a-benzyl-2-methyl-3-methylidene-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-1-(benzyloxy)-2-oxoethyl}-2-methylalaninamide 2,3-dihydroxybutanedioate (1:1);2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-3a,4,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-5(3H)-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide (2R,3R)-2,3-dihydroxysuccinate
- 中文名:
- 卡普瑞林酒石酸盐
- 中文别名:
- 酒石酸己罗莫林;酒石酸卡莫瑞林;卡普瑞林酒石酸盐;卡普瑞林L-酒石酸盐
- CBNumber:
- CB02611352
- 分子式:
- C32H41N5O10
- 分子量:
- 655.71
- MOL File:
- 193273-69-7.mol
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卡普瑞林酒石酸盐化学性质
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熔点:
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>150oC (dec.)
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储存条件:
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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溶解度:
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DMSO (Slightly), Methanol (Slightly)
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形态:
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Solid
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颜色:
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White to Light Yellow
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稳定性:
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Hygroscopic
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卡普瑞林酒石酸盐性质、用途与生产工艺
Capromorelin Tartrate 是一种可口服的，有效的growth hormone secretagogue receptor (GHSR)激动剂，对hGHS-R1a的Ki值为 7 nM。
Capromorelin stimulates GH release in rat pituitary cell cultures with EC
50
of 3 nM.
Dogs receiving capromorelin (30 mg/mL) have food consumption that is significantly greater than dogs treated with placebo. All dogs in the capromorelin group gain weight by 0.52 kg, more than that of placebo group. Capromorelin shows enhanced intestinal absorption in rodent models and exhibits superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. Capromorelin stimulates GH release in anesthesized rat model, with ED
50
of 0.05 mg/kg iv.
卡普瑞林酒石酸盐
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-15243 | 卡普瑞林酒石酸盐
Capromorelin Tartrate | 193273-69-7 | 2mg | 500元 |
| 2024/04/30 | HY-15243 | 卡普瑞林酒石酸盐
Capromorelin Tartrate | 193273-69-7 | 10mM * 1mLin DMSO | 1010元 |
193273-69-7, 卡普瑞林酒石酸盐 相关搜索:
- API
- 药靶配体
- C28H35N5O4C4H6O6
- 酒石酸己罗莫林
- 卡普瑞林L-酒石酸盐
- 卡普瑞林酒石酸盐
- 酒石酸卡莫瑞林
- 193273-69-7
- 2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-3a,4,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-5(3H)-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide (2R,3R)-2,3-dihydroxysuccinate
- Inhibitor,Growth hormone secretagogue receptor,GHSR,Capromorelin,inhibit,Capromorelin Tartrate
- CP 424391-18; CP-424391 TARTRATE
- CP-424391 tartrate
- CS-2136
- N-{2-[(3aS)-3a-benzyl-2-methyl-3-methylidene-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-1-(benzyloxy)-2-oxoethyl}-2-methylalaninamide 2,3-dihydroxybutanedioate (1:1)
- Capromorelin tartrate (CP-424,391)
- CP 424391-18
- CaproMorelin Tartrate