罗卡斯汀
|
|
|
- CAS号:
- 91833-49-7
- 英文名:
- 2-[2-(Dimethylamino)ethyl]-3,4-dihydro-4-methylpyrido[3,2-f]-1,4-oxazepine-5(2H)-thione
- 英文别名:
- 2-[2-(Dimethylamino)ethyl]-3,4-dihydro-4-methylpyrido[3,2-f]-1,4-oxazepine-5(2H)-thione;2-[2-(Dimethylamino)ethyl]-3,4-dihydro-4-methylpyrido[3,2-f][1,4]oxazepine-5(2H)-thione;Pyrido[3,2-f]-1,4-oxazepine-5(2H)-thione, 2-[2-(dimethylamino)ethyl]-3,4-dihydro-4-methyl-
- 中文名:
- 罗卡斯汀
- 中文别名:
- 罗卡斯汀;化合物 T16778
- CBNumber:
- CB12199778
- 分子式:
- C13H19N3OS
- 分子量:
- 265.37
- MOL File:
- 91833-49-7.mol
|
|
|
罗卡斯汀化学性质
-
熔点:
-
130-133 °C
-
|
-
沸点:
-
379.0±52.0 °C(Predicted)
-
|
-
密度:
-
1.20±0.1 g/cm3(Predicted)
-
|
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
-
酸度系数(pKa):
-
9.18±0.28(Predicted)
-
|
罗卡斯汀性质、用途与生产工艺
Rocastine 是一种选择性的，非镇静的 H1 拮抗剂，为抗组胺剂。
Rocastine is effective with a 15 min pretreatment time (PD
50
= 0.13 mg/kg) as it is with a 1 hr pretreatment time (PD
50
= 0.12 mg/kg). Rocastine protects guinea pigs from collapse induced by aerosolized antigen; rocastine is approximately 36x more potent than diphenhydramine and as potent as oxatomide and terfenadine. Rocastine does not alter the EEG of cats at doses in vast excess (150x) of its antihistaminic dose nor does it potentiate yohimbine toxicity in mice.
罗卡斯汀
上下游产品信息
上游原料
下游产品
91833-49-7, 罗卡斯汀 相关搜索:
- 化合物 T16778
- 罗卡斯汀
- 91833-49-7
- Pyrido[3,2-f]-1,4-oxazepine-5(2H)-thione, 2-[2-(dimethylamino)ethyl]-3,4-dihydro-4-methyl-
- 2-[2-(Dimethylamino)ethyl]-3,4-dihydro-4-methylpyrido[3,2-f]-1,4-oxazepine-5(2H)-thione
- 2-[2-(Dimethylamino)ethyl]-3,4-dihydro-4-methylpyrido[3,2-f][1,4]oxazepine-5(2H)-thione