柴胡皂苷元A
|
|
|
- CAS号:
- 5092-09-1
- 英文名:
- saikogenin A
- 英文别名:
- Clinopodiside A1;Oleana-11,13(18)-diene-3,16,23,28-tetrol, (3β,4α,16β)-;Saikogenin A,inhibit,Inhibitor,DPP,1166100,Dipeptidyl Peptidase
- 中文名:
- 柴胡皂苷元A
- 中文别名:
- 柴胡皂苷元A 标准品
- CBNumber:
- CB21340129
- 分子式:
- C30H48O4
- 分子量:
- 472.7
- MOL File:
- 5092-09-1.mol
|
|
|
柴胡皂苷元A化学性质
-
熔点:
-
287-293 °C
-
|
-
沸点:
-
607.4±55.0 °C(Predicted)
-
|
-
密度:
-
1.16±0.1 g/cm3(Predicted)
-
|
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
-
酸度系数(pKa):
-
14.47±0.70(Predicted)
-
|
柴胡皂苷元A性质、用途与生产工艺
Saikogenin A 可从中药柴胡中提取，是一种二肽基肽酶 IV (DPP-IV) 抑制剂。
Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide.
Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation.
柴胡皂苷元A
上下游产品信息
上游原料
下游产品
5092-09-1, 柴胡皂苷元A 相关搜索:
- 标准品，对照品
- 对照品
- 新品
- 标准品-对照品
- 中药对照品
- 对照品
- 柴胡皂苷元A 标准品
- 5092-09-1
- Saikogenin A,inhibit,Inhibitor,DPP,1166100,Dipeptidyl Peptidase
- Clinopodiside A1
- Oleana-11,13(18)-diene-3,16,23,28-tetrol, (3β,4α,16β)-