ChemicalBook
English   Japanese   Germany   Korea

网站主页 >> CAS数据库列表 >> Tritoqualine

Tritoqualine

生物活性 靶点 体外研究 体内研究

Tritoqualine, 14504-73-5, 结构式
Tritoqualine
CAS号:
14504-73-5
英文名:
Tritoqualine
英文别名:
Tritocalin;Hypostamine;Inhibostamin;7-Amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 7-amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-
中文名:
Tritoqualine
中文别名:
酞茂异喹;化合物 T17166
CBNumber:
CB31180009
分子式:
C26H32N2O8
分子量:
500.54
MOL File:
14504-73-5.mol

Tritoqualine化学性质

熔点:
183°
沸点:
647.2±55.0 °C(Predicted)
密度:
1.296±0.06 g/cm3(Predicted)
储存条件:
Store at -20°C
溶解度:
Soluble in DMSO
酸度系数(pKa):
6.22±0.40(Predicted)
安全信息

Tritoqualine性质、用途与生产工艺

生物活性

Tritoqualine 是一种组氨酸脱羧酶抑制剂。

靶点

histidine decarboxylase

体外研究

The effect of Tritoqualine (TRQ) on the CCl 4 -induced enzyme leakage is investigated by pretreatment of rats with Tritoqualine (200 mg/kg/day, p.o., 7 days). The ratio of lactate dehydrogenase (LDH) release from the cells of Tritoqualine-pretreated rats is significantly less than that in control rats. The rate of malondialdehyde (MDA) production is accelerated after the addition of 7.8 mM CCl 4 . Tritoqualine reduces its rate in a dose dependent manner, and it completely prevents CCl 4 -stimulated lipid peroxidation at a concentration of 33 μM.

体内研究

A single administration of CCl 4 (0.75 mL/kg, p.o.) causes a five-fold increase of in vivo lipid peroxidation in the liver. In contrast, a reduction of 37% in the lipid peroxidation is obtained by Tritoqualine (100 mg/kg) pretreatment for 14 days prior to CCl 4 treatment. A 63% reduction is observed in vitamin E (25 mg/kg) pretreated rats.

Tritoqualine 上下游产品信息

上游原料

下游产品

Tritoqualine 生产厂家

全球有 12家供应商   Tritoqualine国内生产厂家
供应商联系电话电子邮件国家产品数优势度
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn 美国 4863 58
四川省维克奇生物科技有限公司 028-81700200 18116577057 3003855609@qq.com 中国 7892 56
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 marketing@targetmol.com 美国 19892 58
安耐吉化学&3A（安徽泽升科技有限公司） 021-58432009 400-005-6266 marketing1@energy-chemical.com 中国 44843 58
天津普西唐生物医药科技有限公司 010-60605840 psaitong@jm-bio.com 中国 29778 58
成都普思生物科技股份有限公司 18080489829 3004654993@qq.com 中国 9209 58
TargetMol中国（陶术生物） 4008200310 marketing@tsbiochem.com 中国 24017 58
LEAPCHEM CO., LTD. +86-852-30606658 market18@leapchem.com 中国 43348 58
 

14504-73-5, Tritoqualine 相关搜索:

3-羟基-2-氨基苯甲酸 2-氨基-3,4,5-三甲氧基苯甲酸 3,4,5-三甲氧基苯甲酸 2-乙基-3-甲氧基苯甲酸 2-氨基-4,5-二甲氧基苯甲酸乙酯 2-氨基-4,5-二甲氧基苯甲酸甲酯 2-氨基-3-甲氧基苯甲酸 2-苯乙基苯甲酸 甲氧那明 3,4-二乙氧基苯甲酸 3,4,5-三甲氧基氨基苯甲酸甲酯 2-氨基-5-甲氧基苯甲酸甲酯
  • C26H32N2O8
  • 化合物 T17166
  • 酞茂异喹
  • 14504-73-5
  • 1(3H)-Isobenzofuranone, 7-amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-
  • Tritocalin
  • Inhibostamin
  • Hypostamine
  • 7-Amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one
Copyright 2016 © ChemicalBook. All rights reserved