VEGFR2 KISE INHIBITOR I
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- CAS号:
- 15966-93-5
- 英文名:
- VEGFR2 Kinase Inhibitor I
- 英文别名:
- SU5408;VEGFR2 TK Inhibitor;SU 5408;SU-5408;SU5408;VEGFR2 KISE INHIBITOR I;VEGFR2 Kinase Inhibitor I;VEGFR2 kinase inhibitor I(SU-5408);Research Grade Ramucirumab(DHE16601);SU5408,Vascular endothelial growth factor receptor,SU-5408,Inhibitor,VEGFR,SU 5408,inhibit;1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester
- 中文名:
- VEGFR2 KISE INHIBITOR I
- 中文别名:
- VEGFR2激酶抑制剂I;RAMUCIRUMAB ( 雷莫芦单抗 );化合物VEGFR2 KINASE INHIBITOR I;2,4-二甲基-5-((2-氧吲哚-3-亚甲基)甲基)-1H-吡咯-3-羧酸乙酯
- CBNumber:
- CB32501836
- 分子式:
- C18H18N2O3
- 分子量:
- 310.35
- MOL File:
- 15966-93-5.mol
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VEGFR2 KISE INHIBITOR I化学性质
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沸点:
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571.4±50.0 °C(Predicted)
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密度:
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1.271±0.06 g/cm3(Predicted)
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储存条件:
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Sealed in dry,Store in freezer, under -20°C
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溶解度:
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DMF: 1 mg/ml; DMSO: 1 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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12.40±0.20(Predicted)
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VEGFR2 KISE INHIBITOR I性质、用途与生产工艺
SU5408 (VEGFR2 Kinase Inhibitor I)是一种有效、选择性 VEGFR2 Kinase抑制剂，IC50为70 nM。
| Target | Value |
VEGFR2
(Cell-free assay)
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70 nM
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3-Substituted indolin-2-ones have been designed and synthesized as a novel class of tyrosine kinase inhibitors which exhibit selectivity toward different receptor tyrosine kinases (RTKs). These compounds have been evaluated for their relative inhibitory properties against a panel of RTKs in intact cells. SU5408 (VEGFR2 Kinase Inhibitor I) is found to be the most potent and selective VEGFR2 inhibitor among the compounds. SU5408 (VEGFR2 Kinase Inhibitor I) shows little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC
50
>100 µM).
VEGFR2 KISE INHIBITOR I
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-103002 | VEGFR2 KISE INHIBITOR I
SU5408 | 15966-93-5 | 1 mg | 800元 |
| 2024/04/30 | HY-103002 | VEGFR2 KISE INHIBITOR I
SU5408 | 15966-93-5 | 5mg | 2400元 |
VEGFR2 KISE INHIBITOR I
生产厂家
15966-93-5, VEGFR2 KISE INHIBITOR I 相关搜索:
- Angiogenesis and Metastasis
- Growth Factors and Cytokines
- 合成有机化合物配体
- VEGFR2激酶抑制剂I
- 化合物VEGFR2 KINASE INHIBITOR I
- 2,4-二甲基-5-((2-氧吲哚-3-亚甲基)甲基)-1H-吡咯-3-羧酸乙酯
- RAMUCIRUMAB ( 雷莫芦单抗 )
- 15966-93-5
- SU5408,Vascular endothelial growth factor receptor,SU-5408,Inhibitor,VEGFR,SU 5408,inhibit
- Research Grade Ramucirumab(DHE16601)
- 1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester
- VEGFR2 kinase inhibitor I(SU-5408)
- SU 5408;SU-5408;SU5408
- VEGFR2 TK Inhibitor
- VEGFR2 Kinase Inhibitor I
- VEGFR2 KISE INHIBITOR I
- SU5408