CX691
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- CAS号:
- 211735-76-1
- 英文名:
- FARAMPATOR
- 英文别名:
- CX 691;Org2444;Org 24448;FARAMPATOR;CX-691; ORG2444;Org24448, CX-691;Farampator (CX691）;Farampator (CX-691, Org24448);CX 691; ORG 24448; CX-691; CX691;Methanone, 2,1,3-benzoxadiazol-5-yl-1-piperidinyl-
- 中文名:
- CX691
- 中文别名:
- 化合物FARAMPATOR;苯并[C][1,2,5]恶二唑-5-基(哌啶-1-基)甲酮
- CBNumber:
- CB41011735
- 分子式:
- C12H13N3O2
- 分子量:
- 231.25
- MOL File:
- 211735-76-1.mol
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CX691化学性质
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沸点:
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398.3±34.0 °C(Predicted)
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密度:
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1.299±0.06 g/cm3(Predicted)
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储存条件:
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Sealed in dry,Store in freezer, under -20°C
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溶解度:
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DMF: 30 mg/ml; DMF:PBS (pH7.2) (1:40): 25μg/ml; DMSO: 20 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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-1.33±0.36(Predicted)
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CX691性质、用途与生产工艺
Farampator (CX-691;Org24448) 是一种AMPA受体正调节剂。
Farampator has potential in treating disorders characterised by cognitive deficits such as Alzheimer's disease and schizophrenia. CX691 attenuates a scopolamine-induced impairment of cued fear conditioning following acute administration (0.1 mg/kg p.o.) and a temporally induced deficit in novel object recognition following both acute (0.1 and 1.0 mg/kg p.o.) and sub-chronic (bi-daily for 7 days) administration (0.01, 0.03, 0.1 mg/kg p.o.). It also improves attentional set-shifting following sub-chronic administration (0.3 mg/kg p.o.). Farampator (500 mg) unequivocally improves short-term memory but appeares to impair episodic memory. Furthermore, it tends to decrease the number of switching errors in the CTMT. Drug-induced side effects (SEs) included headache, somnolence and nausea. Subjects with SEs has significantly higher plasma levels of farampator than subjects without SEs.
CX691
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-10937 | Farampator | | 1 mg | 453元 |
| 2024/04/30 | HY-10937 | CX691
Farampator | 211735-76-1 | 5mg | 900元 |
211735-76-1, CX691 相关搜索:
- 药靶配体
- 苯并[C][1,2,5]恶二唑-5-基(哌啶-1-基)甲酮
- 化合物FARAMPATOR
- 211735-76-1
- Benzo[c][1,2,5]oxadiazol-5-yl(piperidin-1-yl)methanone
- CX 691,CX691,Farampator,inhibit,Org 24448,Org-24448,Inhibitor,iGluR,Ionotropic glutamate receptors
- Farampator (CX-691, Org24448)
- Farampator (CX691）
- Org24448, CX-691
- Methanone, 2,1,3-benzoxadiazol-5-yl-1-piperidinyl-
- CX 691; ORG 24448; CX-691; CX691
- Org2444
- CX-691; ORG2444
- FARAMPATOR
- Org 24448
- CX 691