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4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate, 68483-33-0, 结构式
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
CAS号:
68483-33-0
英文名:
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
英文别名:
apyramide;4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester;1-(4-Chlorobenzoyl)-2-methyl-5-methoxy-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester;1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(acetylamino)phenyl ester
中文名:
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
中文别名:
化合物 T10355;化合物APYRAMIDE
CBNumber:
CB4909264
分子式:
C27H23ClN2O5
分子量:
490.93
MOL File:
68483-33-0.mol

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate化学性质

熔点:
145-150 °C(Solv: benzene (71-43-2); methanol (67-56-1))
沸点:
671.1±55.0 °C(Predicted)
密度:
1.29±0.1 g/cm3(Predicted)
储存条件:
Store at -20°C
溶解度:
Soluble in DMSO
酸度系数(pKa):
14.20±0.70(Predicted)
安全信息

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate性质、用途与生产工艺

生物活性

Apyramide 是一种抗炎试剂 (NSAID),是吲哚美辛 (HY-14397) 的前药。Indomethacin 是一种强效的、血脑通透的、非选择性的 COX1 和 COX2 抑制剂。

体内研究

Apyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities.

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate 上下游产品信息

上游原料

下游产品

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate 试剂级价格

更新日期产品编号产品名称CAS编号包装价格
2024/04/30HY-U000464-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
Apyramide
68483-33-05mg2000元
2024/04/30HY-U000464-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
Apyramide
68483-33-010mg3400元

4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate 生产厂家

供应商联系电话电子邮件国家产品数优势度
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn 美国 4863 58
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 marketing@targetmol.com 美国 19892 58
ChemeGen 中国 18818260767 sales@chemegen.com 中国 11289 58
TargetMol中国(陶术生物) 4008200310 marketing@tsbiochem.com 中国 24018 58
上海陌孚医药科技有限公司 021-59167510 18117107507 vip@med-life.cn 中国 5019 58
銳迪國際科技有限公司 18024082417 market@ubiochem.com 中国 9180 58
 

68483-33-0, 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate 相关搜索:

  • 化合物APYRAMIDE
  • 化合物 T10355
  • 68483-33-0
  • 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(acetylamino)phenyl ester
  • 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester
  • 1-(4-Chlorobenzoyl)-2-methyl-5-methoxy-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester
  • apyramide
  • 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
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