(3S,5S)-阿伐他汀钠盐
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- CAS号:
- 501121-34-2
- 英文名:
- (3S,5S)-Atorvastatin sodium salt
- 英文别名:
- S,S-Atorvastatin;Atorvastatin lysine;ent-Atorvastatin Sodium;3S,5S-Atorvastatin Sodium;Atorvastatin EP Impurity E;S,S-Atorvastatin Sodium Salt;(3S,5S)-7-(2-(4-fluorophenyl)-;(3S,5S)-Atorvastatin Sodium Salt;Atorvastatin EP imp E (Free Acid);Atorvastatin USP Related CoMpound E
- 中文名:
- (3S,5S)-阿伐他汀钠盐
- 中文别名:
- 阿伐他汀钠盐;阿托伐他汀EP杂质E;3S,5S)-阿托伐他汀;阿托伐他汀钙杂质E(单体);阿托伐他汀USP相关物质E;USP阿托伐他汀相关化合物E;阿托伐他汀USP相关化合物E;(3S,5S)-阿伐他汀钠盐;USP阿托伐抑制素相关化合物E;阿托伐他汀杂质25(阿托伐他汀EP杂质E)
- CBNumber:
- CB71176778
- 分子式:
- C33H35FN2O5
- 分子量:
- 558.64
- MOL File:
- 501121-34-2.mol
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(3S,5S)-阿伐他汀钠盐化学性质
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熔点:
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182-184°C
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储存条件:
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-20°C Freezer
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溶解度:
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DMSO (Slightly), Methanol (Slightly)
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形态:
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Solid
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颜色:
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White
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稳定性:
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Hygroscopic
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(3S,5S)-阿伐他汀钠盐性质、用途与生产工艺
(3S,5S)-Atorvastatin 是 Atorvastatin 的无活性对映异构体。(3S,5S)-Atorvastatin 可以激活孕烷 X 受体 (PXR)。Atorvastatin 是一种具有口服活性的 HMG-CoA 还原酶抑制剂，具有有效降低血脂的能力。
Pregnane X receptor (PXR)
Atorvastatin and its inactive enantiomer (3S,5S)-Atorvastatin increases CYP2B and CYP3A mRNA content with equal ability.
(3S,5S)-Atorvastatin in 100 μM concentrations induces luciferase activity with an EC
50
of 12.4 μM.
Addition of (3S,5S)-Atorvastatin to the 2-formylphenylboronic
acid (FPBA)/l-tryptophanol mixture induces an intensity enhancement of l-tryptophanol florescence.
(3S,5S)-阿伐他汀钠盐
上下游产品信息
上游原料
下游产品
501121-34-2, (3S,5S)-阿伐他汀钠盐 相关搜索:
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Inhibitors
- Pfizer compounds
- Chiral Reagents
- Aromatics
- 杂质对照品
- 对照品-杂质对照品
- C33H34FN2NaO5
- USP阿托伐抑制素相关化合物E
- 阿托伐他汀杂质25(阿托伐他汀EP杂质E)
- USP阿托伐他汀相关化合物E
- 阿托伐他汀USP相关化合物E
- (3S,5S)-阿伐他汀钠盐
- 3S,5S)-阿托伐他汀
- 阿托伐他汀钙杂质E(单体)
- 阿托伐他汀EP杂质E
- 阿托伐他汀USP相关物质E
- 阿伐他汀钠盐
- 501121-34-2
- Atorvastatin lysine
- Atorvastatin EP Impurity E (Na Salt)
- (3S,5S)-7-[3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid sodium salt
- ent-Atorvastatin Sodium
- Atorvastatin Impurity 25（Atorvastatin EP Impurity E）
- Atorvastatin EP imp E (Free Acid)
- (3S,5S)-7-(2-(4-fluorophenyl)-
- Atorvastatin Calcium Hydrate impurity E
- S,S-Atorvastatin Sodium Salt
- 3S,5S-Atorvastatin Sodium
- (S,dS)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βS,δS)-
- S,S-Atorvastatin
- (3S,5S)-Atorvastatin Sodium Salt
- Atorvastatin USP Related CoMpound E
- (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid SodiuM
- (bS,dS)-2-(4-Fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
- Atorvastatin EP Impurity E